Femtocell is featured with a low-power and low-cost cellular access in indoor environments, and thus offers an effective yet flexible way to implement information exchange over Internet of Things. In femtocell networks, the dense deployment of home eNodeBs causes severe inter-cell interferences and imposes heavier load on the scarce frequency spectrum. In this paper, we propose an inter-femtocell interference coordination scheme to enable random and fractional reuse of frequency resources in a 3D in-building scenario. Specifically, we consider the regular femtocell deployment, where all the femtocells are divided into two groups and two neighboring femtocells will be classified into different group. Each group is initially allocated with a half of frequency resources. To more sufficiently utilize the spectrum, either group of femtocell is allowed to transmit over the frequency assigned to the other group of femtocell in a random way at the cost of introducing some interferences, i.e., reuse based on a specified probability. This probability is determined by maximizing the geometric mean of users’ average throughput, such that the fairness among users is guaranteed simultaneously. Moreover, an equivalent scheme generated from full frequency reuse between two femtocells groups is also given. Here, either group of femtocell will avoid transmitting over fractional frequency randomly with a certain probability and the interference to the adjacent femtocell can be reduced. The simulation results show that the proposed schemes could obtain the larger system average rate and edge user performance compared with the baseline schemes. Moreover, the geometrical average throughput per user achieved by our method is highest, and a more fair resources allocation can be realized .