The Conners' Continuous Performance Test (CPT) is a neuropsychological task that has repeatedly been shown to differentiate ADHD from normal groups. Several variables may be derived from the Conners' CPT including errors of omission and commission, mean hit reaction time(RT), mean hit RT standard error, d', and β. What each CPT parameter actually assesses has largely been based upon clinical assumptions and the face validity of each measure (e.g., omission errors measure inattention, commission errors measure impulsivity). This study attempts to examine relations between various CPT variables and phenotypic behaviors so as to better understand the various CPT variables. An epidemiological sample of 817 children was administered the Conners' CPT. Diagnostic interviews were conducted with parents to determine ADHD symptom profiles for all children. Children diagnosed with ADHD had more variable RTs, made more errors of commission and omission, and demonstrated poorer perceptual sensitivity than nondiagnosed children. Regarding specific symptoms, generalized estimating equations (GEE) and ANCOVAs were conducted to determine specific relationships between the 18 DSM-IV ADHD symptoms and 6 CPT parameters. CPT performance measures demonstrated significant relationships to ADHD symptoms but did not demonstrate symptom domain specificity according to a priori assumptions. Overall performance on the two signal detection measures, d' and β, was highly related to all ADHD symptoms across symptom domains. Further, increased variability in RTs over time was related to most ADHD symptoms. Finally, it appears that at least 1 CPT variable, mean hit RT, is minimally related to ADHD symptoms as a whole, but does demonstrate some specificity in its link with symptoms of hyperactivity.
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VET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USAVET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USA
Epstein, JI
Keefe, RSE
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VET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USAVET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USA
Keefe, RSE
Roitman, SL
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VET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USAVET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USA
Roitman, SL
Harvey, PD
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VET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USAVET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USA
Harvey, PD
Mohs, RC
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VET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USAVET ADM MED CTR, PSYCHIAT SERV 116A, MT SINAI MED CTR, DEPT PSYCHIAT, BRONX, NY 10468 USA
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Geha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel
Tel Aviv Univ, Sch Continuous Med Educ, Sackler Sch Med, Tel Aviv, Israel
Tel Aviv Univ, Sackler Sch Med, Tel Aviv, IsraelGeha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel
Peskin, Miriam
Sommerfeld, Eliane
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Geha Mental Hlth Ctr, Petah Tiqwa, Israel
Ariel Univ, Dept Psychol, Ariel, IsraelGeha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel
Sommerfeld, Eliane
Basford, Yael
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Geha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, IsraelGeha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel
Basford, Yael
Rozen, Shlomit
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Geha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, IsraelGeha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel
Rozen, Shlomit
Zalsman, Gil
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Geha Mental Hlth Ctr, Petah Tiqwa, Israel
Tel Aviv Univ, Tel Aviv, Israel
Columbia Univ, Neurosci Dept, New York State Psychiat Inst, New York, NY USAGeha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel
Zalsman, Gil
Weizman, Abraham
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Geha Mental Hlth Ctr, Petah Tiqwa, Israel
Geha Mental Hlth Ctr, Lab Biol Psychiat, Petah Tiqwa, Israel
Geha Mental Hlth Ctr, Res Unit, Petah Tiqwa, Israel
Tel Aviv Univ, Child & Adult Psychiat, Sackler Fac Med, Tel Aviv, Israel
Felsenstein Med Res Ctr, Petah Tiqwa, IsraelGeha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel
Weizman, Abraham
Manor, Iris
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Geha Mental Hlth Ctr, ADHD Unit, Petah Tiqwa, Israel
Tel Aviv Univ, Psychiat, Sackler Fac Med, Tel Aviv, IsraelGeha Mental Hlth Ctr, Young Children Div, Petah Tiqwa, Israel