Verification of EZH2 as a druggable target in metastatic uveal melanoma

被引:0
|
作者
Bei Jin
Ping Zhang
Hailin Zou
Huijing Ye
Yun Wang
Jing Zhang
Huasheng Yang
Jingxuan Pan
机构
[1] Sun Yat-sen University,State Key Laboratory of Ophthalmology, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Zhongshan Ophthalmic Center
来源
关键词
Uveal melanoma; EZH2; Hepatic metastasis; Motility; Cancer stem-like cells;
D O I
暂无
中图分类号
学科分类号
摘要
引用
下载
收藏
相关论文
共 50 条
  • [41] EZH2 as a potential therapeutic target for gastrointestinal cancers
    Hashemi, Mehrdad
    Nazdari, Naghmeh
    Gholamiyan, Ghazaleh
    Paskeh, Mahshid Deldar Abad
    Jafari, Ali Moghadas
    Nemati, Fateme
    Khodaei, Elaheh
    Abyari, Ghazal
    Behdadfar, Nazanin
    Raei, Behnaz
    Raesi, Rasoul
    Nabavi, Noushin
    Hu, Peng
    Rashidi, Mohsen
    Taheriazam, Afshin
    Entezari, Malihe
    PATHOLOGY RESEARCH AND PRACTICE, 2024, 253
  • [42] The epigenetic modifier EZH2 represses antitumor immunity in melanoma
    Tiffen, Jessamy
    Shklovskaya, Elena
    Gallagher, Stuart
    Gunatilake, Dilini
    Hersey, Peter
    CANCER RESEARCH, 2018, 78 (13)
  • [43] Expression of polycomb group protein EZH2 in nevi and melanoma
    McHugh, Jonathan B.
    Fullen, Douglas R.
    Ma, Linglei
    Kleer, Celina G.
    Su, Lyndon D.
    JOURNAL OF CUTANEOUS PATHOLOGY, 2007, 34 (08) : 597 - 600
  • [44] Role of EZH2 histone methyltrasferase in melanoma progression and metastasis
    Mahmoud, Fade
    Shields, Bradley
    Makhoul, Issam
    Hutchins, Laura F.
    Shalin, Sara C.
    Tackett, Alan J.
    CANCER BIOLOGY & THERAPY, 2016, 17 (06) : 579 - 591
  • [45] lncRNA SNHG7 affects malignant tumor behaviors through downregulation of EZH2 in uveal melanoma cell lines
    Wu, Xue
    Yuan, Yiqun
    Ma, Ruiqi
    Xu, Binbin
    Zhang, Rui
    ONCOLOGY LETTERS, 2020, 19 (02) : 1505 - 1515
  • [46] Inhibition of SIRT1 Increases EZH2 Protein Level and Enhances the Repression of EZH2 on Target Gene Expression
    Chih-chuan Liang
    Chinese Medical Sciences Journal, 2011, 26 (02) : 77 - 84
  • [47] Role of the EZH2 histone methyltransferase as a therapeutic target in cancer
    Italiano, Antoine
    PHARMACOLOGY & THERAPEUTICS, 2016, 165 : 26 - 31
  • [48] Histone Methyltransferase EZH2: A Therapeutic Target for Ovarian Cancer
    Jones, Bayley A.
    Varambally, Sooryanarayana
    Arend, Rebecca C.
    MOLECULAR CANCER THERAPEUTICS, 2018, 17 (03) : 591 - 602
  • [49] Exploring the role of EZH2 (PRC2) as epigenetic target
    Aier, Imlimaong
    Raj, Utkarsh
    2016 INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND SYSTEMS BIOLOGY (BSB), 2016,
  • [50] EZH2 Expression in Rhabdomyosarcoma: A Potential Biomarker and Therapeutic Target
    Wang, Qian
    Shapiro, Kate
    Lu, Yong
    Shroyer, Kenneth
    Hwang, Sonya
    MODERN PATHOLOGY, 2019, 32