Synthesis and study of antibacterial and antifungal activities of Novel 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl] acetylamino]thiazoles

被引：0

作者：

Zafer Asim Kaplancikli

Gülhan Turan-Zitouni

Gilbert Revial

Kiymet Guven

机构：

[1] CNRS (ESA 7084) ESPCI,Laboiratoire de Chimie Organique

[2] Anadolu University,Department of Biology

[3] Faculty of Science,Department of Pharmaceutical Chemistry

[4] Anadolu University,undefined

[5] Faculty of Pharmacy,undefined

来源：

Archives of Pharmacal Research | 2004年 / 27卷

关键词：

Thiazole; Benzoxazole; Benzimidazole; Antimicrobial activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Several 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl]acetylamino]thiazoles derivatives were synthesized by reacting 4-substituted-2-(chloroacetylamino)thiazoles with benzoxazole/benzimidazole-2-thioles in acetone and in the presence of K2CO3. The chemical structures of the compounds were elucidated by IR,1H-NMR, and FAB+-MS spectral data. Their antimicrobial activities againstMicrococcus luteus (NRLL B-4375),Bacillus cereus (NRRL B-3711),Proteus vulgaris (NRRL B-123),Salmonella typhimurium (NRRL B-4420),Staphylococcus aureus (NRRL B-767),Escherichia coli (NRRL B-3704),Candida albicans and Candida globrata (isolates obtained from Osmangazi Uni. Fac.of Medicine) were investigated and in this investigation, a significant level of activity was illustrated.

引用

页码：1081 / 1085

页数：4

共 50 条

[31] Novel Antimicrobial Agents: Fluorinated 2-(3-(Benzofuran-2-yl) pyrazol-1-yl) thiazoles
Mohamed, Hanan A.
Abdel-Latif, Ehab
Abdel-Wahab, Bakr F.
Awad, Ghada E. A.
INTERNATIONAL JOURNAL OF MEDICINAL CHEMISTRY, 2013, 2013
[32] Synthesis, Characterization, DFT Study and Antifungal Activities of Some Novel 2-(Phenyldiazenyl)phenol Based Azo Dyes
Marinescu, Maria
Popa, Claudia Valentina
Tanase, Maria Antonia
Soare, Andreia Cristina
Tablet, Cristina
Bala, Daniela
Cinteza, Ludmila Otilia
Ditu, Lia Mara
Gifu, Ioana Catalina
Petcu, Cristian
MATERIALS, 2022, 15 (22)
[33] Synthesis of 2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetamides
A. K. Shiryaev
A. M. Gulyaeva
V. A. Shiryaev
U. M. Aristova
Russian Journal of Organic Chemistry, 2023, 59 : 738 - 742
[34] Design, Synthesis, Antibacterial and Antifungal Activity of Novel 2-[(E)-2-aryl-1-ethenyl]-3-(2-sulfanyl-1H-benzo[d]imidazole-5-yl)-3,4-dihydro-4-quinolinones
Nath, Anisetti Ravinder
Reddy, Malladi Srinivas
E-JOURNAL OF CHEMISTRY, 2012, 9 (03) : 1481 - 1489
[35] Synthesis of 2-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-2-yl)sulfanyl]acetamides
Shiryaev, A. K.
Gulyaeva, A. M.
Shiryaev, V. A.
Aristova, U. M.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2023, 59 (04) : 738 - 742
[36] SYNTHESIS OF 2-(2-PYRIDYL) QUINOLINES PROMOTED BY MICROWAVES AND THEIR ANTIFUNGAL ACTIVITIES
Borel, Carmindo R.
Barbosa, Luiz C. A.
Maltha, Celia R. A.
Fernandes, Sergio A.
Santos, Larissa B.
Takahashi, Jacqueline A.
QUIMICA NOVA, 2017, 40 (09): : 1065 - 1073
[37] Synthesis of Novel Combined Heterocyclic Systems Derived from 2-[(2-Methylquinolin4-yl)sulfanyl]acetohydrazides Substituted in the Benzene Ring
Aleksanyan, I. L.
Hambardzumyan, L. P.
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2020, 56 (02) : 265 - 268
[38] Synthesis of Novel Combined Heterocyclic Systems Derived from 2-[(2-Methylquinolin4-yl)sulfanyl]acetohydrazides Substituted in the Benzene Ring
I. L. Aleksanyan
L. P. Hambardzumyan
Russian Journal of Organic Chemistry, 2020, 56 : 265 - 268
[39] Synthesis and anticonvulsant activities of novel 2-(cyclopentylmethylene)hydrazinyl-1,3-thiazoles in mouse models of seizures
Laczkowski, Krzysztof Z.
Salat, Kinga
Misiura, Konrad
Podkowa, Adrian
Malikowska, Natalia
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2016, 31 (06) : 1576 - 1582
[40] Role of rotamerisation and excited state intramolecular proton transfer in the photophysics of 2-(2′-hydroxyphenyl)benzoxazole, 2-(2′-hydroxyphenyl)benzimidazole and 2-(2′-hydroxyphenyl)benzothiazole:: a theoretical study
Purkayastha, P
Chattopadhyay, N
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2000, 2 (02) : 203 - 210

← 1 2 3 4 5 →