Synthesis and study of antibacterial and antifungal activities of Novel 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl] acetylamino]thiazoles

被引：0

作者：

Zafer Asim Kaplancikli

Gülhan Turan-Zitouni

Gilbert Revial

Kiymet Guven

机构：

[1] CNRS (ESA 7084) ESPCI,Laboiratoire de Chimie Organique

[2] Anadolu University,Department of Biology

[3] Faculty of Science,Department of Pharmaceutical Chemistry

[4] Anadolu University,undefined

[5] Faculty of Pharmacy,undefined

来源：

Archives of Pharmacal Research | 2004年 / 27卷

关键词：

Thiazole; Benzoxazole; Benzimidazole; Antimicrobial activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Several 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl]acetylamino]thiazoles derivatives were synthesized by reacting 4-substituted-2-(chloroacetylamino)thiazoles with benzoxazole/benzimidazole-2-thioles in acetone and in the presence of K2CO3. The chemical structures of the compounds were elucidated by IR,1H-NMR, and FAB+-MS spectral data. Their antimicrobial activities againstMicrococcus luteus (NRLL B-4375),Bacillus cereus (NRRL B-3711),Proteus vulgaris (NRRL B-123),Salmonella typhimurium (NRRL B-4420),Staphylococcus aureus (NRRL B-767),Escherichia coli (NRRL B-3704),Candida albicans and Candida globrata (isolates obtained from Osmangazi Uni. Fac.of Medicine) were investigated and in this investigation, a significant level of activity was illustrated.

引用

页码：1081 / 1085

页数：4

共 50 条

[1] Synthesis and study of antibacterial and antifungal activities of novel 2-[[(benzoxazole/benzimidazole-2-yl)sulfanyl] acetylamino]thiazoles
Kaplancikli, ZA
Turan-Zitouni, G
Revial, G
Guven, K
ARCHIVES OF PHARMACAL RESEARCH, 2004, 27 (11) : 1081 - 1085
[2] Synthesis and Antimicrobial Activity of Methyl 2-(2-(2-Arylquinazolin-4-yl)sulfanyl)acetylamino Alkanoates
Megahed, M. I.
Fathalla, W.
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (12) : 2809 - 2816
[3] Synthesis and crystal structure of ethyl benzimidazole-2-yl phosphonate
胡方中
邹小毛
杨华铮
翁林红
ChineseJournalofChemistry, 2000, (05) : 781 - 785
[4] Synthesis and crystal structure of ethyl benzimidazole-2-yl phosphonate
Hu, FZ
Zou, XM
Yang, HZ
Weng, LH
CHINESE JOURNAL OF CHEMISTRY, 2000, 18 (05) : 781 - 785
[5] Synthesis and study of antibacterial and antifungal activities of novel 1-[2-(benzoxazol-2-yl)ethoxy]-2,6-diarylpiperidin-4-ones
Ramalingan, C
Balasubramanian, S
Kabilan, S
Vasudevan, A
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2004, 39 (06) : 527 - 533
[6] SYNTHESIS OF SOME 2-(ACETOPHENON-HYDRAZIN)-THIAZOLES AND 2-(4-THIAZOLYL-METHYNHYDRAZIN)-THIAZOLES AS POTENTIAL ANTIBACTERIAL AND ANTIFUNGAL AGENTS
Oniga, Ovidiu
Moldovan, Cristina
Oniga, Smaranda
Tiperciuc, Brindusa
Parnau, Adrian
Verite, Philippe
Crisan, Ovidiu
Ionut, Ioana
FARMACIA, 2010, 58 (06) : 825 - 833
[7] Design, Synthesis, Molecular Docking and Biological Evaluation of Novel 2-[(2-{[5-(Pyridin-4-yl)-1, 3, 4-Oxadiazol-2-yl]Sulfanyl}Ethyl)Sulfanyl]-1,3-Benzoxazole
Fathima, Anees
Vagdevi, H. M.
Jayanna, N. D.
Shafeeulla, R. Mohammed
Subbaraju
JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2021, 33 (44A) : 472 - 484
[8] Synthesis, anticonvulsant and antibacterial activities of some novel pyrazolines derived from benzoxazole and benzimidazole
Pujar, Gurubasavaraj V.
Synesh, C.
Purohit, Madhusudan N.
Srinivasalu, N.
Udupi, R. H.
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 17 (04) : 387 - 388
[9] Synthesis and antiprotozoal activity of novel 2-{[2-(1H-imidazol-1-yl)ethyl] sulfanyl}-1H-benzimidazole derivatives
Perez-Villanueva, Jaime
Hernandez-Campos, Alicia
Yepez-Mulia, Lilian
Mendez-Cuesta, Carlos
Mendez-Lucio, Oscar
Hernandez-Luis, Francisco
Castillo, Rafael
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (14) : 4221 - 4224
[10] SYNTHESIS AND PROPERTIES OF 2-AMINO-3-(BENZIMIDAZOLE-2-YL)-1-METHYLQUINOLANE-4
VOLOVENKO, YM
SHOKOL, TV
BABICHEV, FS
UKRAINSKII KHIMICHESKII ZHURNAL, 1986, 52 (07): : 742 - 746

← 1 2 3 4 5 →