Synthesis of 3,3-bis(2-haloethyl) and 3,3,3′-tris(2-haloethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides)

被引：0
|
作者：
T. V. Ternikova
G. V. Pokhvisneva
G. A. Smirnov
P. B. Gordeev
S. V. Nikitin
O. A. Luk’yanov
机构：
[1] Russian Academy of Sciences,N. D. Zelinsky Institute of Organic Chemistry
来源：
Russian Chemical Bulletin | 2017年 / 66卷
关键词：
1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides); 2-haloethyl derivatives; alkylation; acylation; chlorination; bromination; iodination;
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学科分类号：
摘要：
Synthetic procedures towards 3,3-bis(2-haloethyl) and 3,3,3′-tris(2-haloethyl) derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) via halogenation of the corresponding 2-hydroxyethyl derivatives of 1,1′-[methylenebis(oxy)]bis(triaz-1-ene 2-oxides) and iodination of the corresponding 2-bromoethyl derivatives were elaborated. The synthesized compounds are promising NO donors in the living organisms.
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页码：2103 / 2109
页数：6
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