Synthesis, structure and cytotoxic activity of cobalt(II), nickel(II) and copper(II) chloride complexes with acetamidrazones

被引：0

作者：

Gustavo Ponticelli

M. Teresa Cocco

Cenzo Congiu

Valentina Onnis

Sandra Ianelli

Francesco Cossu

机构：

[1] Universita' degli Studi di Cagliari,Dipartimento di Chimica Inorganica ed Analitica

[2] Cittadella di Monserrato,Dipartimento di Tossicologia

[3] Universita' degli Studi di Cagliari,Dipartimento di Chimica Generale ed Inorganica, Chimica Analitica, Chimica Fisica

[4] Universita' di Parma,Istituto di Radiologia, Facoltà di Medicina

[5] Universita' degli Studi di Cagliari,undefined

来源：

Transition Metal Chemistry | 2001年 / 26卷

关键词：

Copper; Nickel; Cobalt; Adenocarcinoma; Cytotoxic Activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

CoII, NiII and CuII chloride complexes with acetamidrazone derivatives (L1)–(L8) have been prepared, by reacting the corresponding metal chloride with the ligand in a 1:2 ratio, and characterised by chemical analysis and physical measurements. The ligand behaviour and the geometry have been assigned on the basis of i.r. spectroscopy, electronic reflectance spectra and molar conductivity values and only, where possible, the geometry has been confirmed as octahedral by X-ray structure determination. Complexes cytotoxicity on a human cellular line of adenocarcinoma was also tested. Three of the complexes present a weak cytotoxicity in vitro.

引用

页码：24 / 27

页数：3

共 50 条

[1] Synthesis, structure and cytotoxic activity of cobalt(II), nickel(II) and copper(II) chloride complexes with acetamidrazones
Ponticelli, G
Cocco, MT
Congiu, C
Onnis, V
Ianelli, S
Cossu, F
[J]. TRANSITION METAL CHEMISTRY, 2001, 26 (1-2) : 24 - 27
[2] Synthesis and structure of new cobalt(II) copper(II), nickel(II) copper(II) and cobalt(II) nickel(II) heteronuclear complexes containing monoethanolamine
Masoud, MS
Motaweh, HA
Ali, AE
[J]. INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY, 2001, 40 (07): : 733 - 737
[3] Synthesis, characterization, and biological activity of cobalt(II), nickel(II), copper(II), and zinc(II) complexes of secnidazole
Betanzos-Lara, Soledad
Gracia-Mora, Isabel
Granada-Macias, Pilar
Flores-Alamo, Marcos
Barba-Behrens, Norah
[J]. INORGANICA CHIMICA ACTA, 2013, 397 : 94 - 100
[4] Metalloantibiotics: Synthesis and antibacterial activity of cobalt(II), copper(II), nickel(II) and zinc(II) complexes of kefzol
Chohan, ZH
Supuran, CT
Scozzafava, A
[J]. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2004, 19 (01) : 79 - 84
[5] STUDY OF THE STRUCTURE OF ANILINE COMPLEXES WITH COBALT(II), NICKEL(II) AND COPPER(II)
MASLENNIKOVA, IS
SAZONOV, AM
AVETIKYAN, GB
[J]. ZHURNAL FIZICHESKOI KHIMII, 1980, 54 (10): : 2451 - 2454
[6] On the electronic structure of chloride bridges in cobalt(II) and nickel(II) complexes
Konovalov, LV
[J]. KOORDINATSIONNAYA KHIMIYA, 1995, 21 (10-11): : 845 - 847
[7] Cobalt(II), nickel(II), and copper(II) complexes with diphenylthiocarbazide
Koksharova, T.V.
Fel'dman, S.V.
[J]. Koordinatsionnaya Khimiya, 2001, 27 (10): : 781 - 784
[8] Cobalt(II), nickel(II), and copper(II) complexes with diphenylthiocarbazide
Koksharova, TV
Fel'dman, SV
[J]. RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2001, 27 (10) : 738 - 740
[9] AMINOPHOSPHINE COMPLEXES OF COPPER(II), COBALT(II) AND NICKEL(II)
SHUKLA, PR
NARAIN, G
[J]. CURRENT SCIENCE, 1978, 47 (07): : 229 - 230
[10] COMPLEXES OF COBALT(II), NICKEL(II) AND COPPER(II) WITH NICOTINE
MURALIDHARAN, S
NAGARAJA, KS
UDUPA, MR
[J]. INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY, 1987, 26 (04): : 348 - 349

← 1 2 3 4 5 →