Scaffolds that mimic antigen-presenting cells enable ex vivo expansion of primary T cells

被引:0
|
作者
Alexander S Cheung
David K Y Zhang
Sandeep T Koshy
David J Mooney
机构
[1] John A. Paulson School of Engineering and Applied Sciences,
[2] Harvard University,undefined
[3] The Wyss Institute for Biologically Inspired Engineering Harvard University,undefined
[4] Harvard-MIT Division of Health Sciences and Technology,undefined
来源
Nature Biotechnology | 2018年 / 36卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
T cells are readily expanded in culture using a system that presents membrane-bound and soluble cues in a natural context.
引用
收藏
页码:160 / 169
页数:9
相关论文
共 50 条
  • [31] Immunogenicity of apoptotic cells in vivo: Role of antigen load, antigen-presenting cells, and cytokines
    Ronchetti, A
    Rovere, P
    Iezzi, G
    Galati, G
    Heltai, S
    Protti, MP
    Garancini, MP
    Manfredi, AA
    Rugarli, C
    Bellone, M
    JOURNAL OF IMMUNOLOGY, 1999, 163 (01): : 130 - 136
  • [32] Cathepsin A is expressed in primary human antigen-presenting cells
    Reich, Michael
    Spindler, Klaus-Dieter
    Burret, Michael
    Kalbacher, Hubert
    Boehm, Bernhard O.
    Burster, Timo
    IMMUNOLOGY LETTERS, 2010, 128 (02) : 143 - 147
  • [33] Ex Vivo Expansion and Activation of Cord Blood Antigen Presenting and Immune Effector Cells
    M S Cairo
    A Abu-Ghosh
    F Bracho
    K Robinson
    E Areman
    P Rhodes
    Pediatric Research, 1999, 45 : 771 - 771
  • [34] Spiny pollen-based antigen-presenting clusters for promoting T cells expansion
    Shou, Xin
    Yu, Yunru
    Wu, Dan
    Wang, Fang
    Sun, Weijian
    Duan, Ping
    Shang, Luoran
    CHEMICAL ENGINEERING JOURNAL, 2022, 437
  • [35] Controlling duration of contact between T cells and antigen-presenting cells
    Kim, S
    Braunstein, NS
    Leonard, EF
    Thomas, JL
    JOURNAL OF IMMUNOLOGICAL METHODS, 2001, 249 (1-2) : 73 - 84
  • [36] ANTIGEN-PRESENTING CELLS AND T-CELL ACTIVATION
    ERB, P
    KENNEDY, M
    WASSMER, P
    HUEGLI, G
    AGENTS AND ACTIONS, 1986, 19 (5-6): : 266 - 268
  • [37] Development of an antigen-presenting bead kit for activation and expansion of human antigen-specific T cells
    Bronevetsky, Yelena
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [38] Evaluation of gammadelta T cells as antigen-presenting cells for cancer immunotherapy
    Yamasaki, A.
    Onishi, H.
    Morisaki, T.
    Tanaka, M.
    Katano, M.
    JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
  • [39] ANTIGEN-PRESENTING CELLS FOR CD8+ T-CELLS
    SPRENT, J
    SCHAEFER, M
    IMMUNOLOGICAL REVIEWS, 1990, 117 : 213 - 234
  • [40] Third antigen-presenting pathway proposed for T cells
    不详
    ASM NEWS, 1996, 62 (09): : 454 - 455