Inhibition of glutamine uptake regulates mTORC1, glutamine metabolism and cell growth in prostate cancer

被引：0

作者：

Qian Wang

Rae-Anne Hardie

Seher Balaban

Mark Schreuder

Andrew Hoy

Michelle van Geldermalsen

Ladan Fazli

Rajini Nagarajah

Charles Bailey

John Rasko

Jeff Holst

机构：

[1] Centenary Institute,Origins of Cancer Laboratory

[2] University of Sydney,Sydney Medical School

[3] University of Sydney,Discipline of Physiology, Bosch Institute

[4] University of Sydney,Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders

[5] University of British Columbia,Department of Urologic Sciences

[6] Centenary Institute,Gene and Stem Cell Therapy Program

[7] Royal Prince Alfred Hospital,Cell and Molecular Therapies

来源：

Cancer & Metabolism | / 2卷 / Suppl 1期

关键词：

Prostate Cancer; Glutamine; Glutamine Metabolism; mTORC1 Signaling; Primary Prostate Cancer;

D O I：

10.1186/2049-3002-2-S1-P27

中图分类号：

学科分类号：

摘要：

引用

共 50 条

[21] ASCT2 regulates glutamine uptake and cell growth in endometrial carcinoma
A D Marshall
M van Geldermalsen
N J Otte
T Lum
M Vellozzi
A Thoeng
A Pang
R Nagarajah
B Zhang
Q Wang
L Anderson
J E J Rasko
J Holst
Oncogenesis, 2017, 6 : e367 - e367
[22] The regulation of cancer cell glutamine metabolism
Lukey, Michael J.
Cerione, Richard A.
TRANSLATIONAL CANCER RESEARCH, 2016, 5 : S1297 - S1298
[23] Cyclosporin A suppresses prostate cancer cell growth through CaMKKβ/AMPK-mediated inhibition of mTORC1 signaling
Lee, Chae Ryun
Chun, Jung Nyeo
Kim, Sang-Yeob
Park, Soonbum
Kim, Su-Hwa
Park, Eun-Jung
Kim, In-San
Cho, Nam-Hyuk
Kim, In-Gyu
So, Insuk
Kim, Tae Woo
Jeon, Ju-Hong
BIOCHEMICAL PHARMACOLOGY, 2012, 84 (04) : 425 - 431
[24] Co-ingestion of glutamine and leucine synergistically promotes mTORC1 activation
Ryoji Yoshimura
Shuichi Nomura
Scientific Reports, 12
[25] Phospholipase D-dependent mTOR complex 1 (mTORC1) activation by glutamine
Bernfeld, Elyssa
Menon, Deepak
Vaghela, Vishaldeep
Zerin, Ismat
Faruque, Promie
Frias, Maria A.
Foster, David A.
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 293 (42) : 16390 - 16401
[26] Glutamine Regulates Cardiac Stem Cell Metabolism and Competency
Salabei, Joshua K.
Lorkiewicz, Pawel K.
Holden, Candice R.
Harbeson, Matthew A.
Li, Qianhong
Bolli, Roberto
Bhatnagar, Aruni
Hill, Bradford G.
CIRCULATION, 2014, 130
[27] Co-ingestion of glutamine and leucine synergistically promotes mTORC1 activation
Yoshimura, Ryoji
Nomura, Shuichi
SCIENTIFIC REPORTS, 2022, 12 (01)
[28] Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1
Tsai, Pei-Yun
Lee, Min-Sik
Jadhav, Unmesh
Naqvi, Insia
Madha, Shariq
Adler, Ashley
Mistry, Meeta
Naumenko, Sergey
Lewis, Caroline A.
Hitchcock, Daniel S.
Roberts, Frederick R.
DelNero, Peter
Hank, Thomas
Honselmann, Kim C.
Oyarvide, Vicente Morales
Mino-Kenudson, Mari
Clish, Clary B.
Shivdasani, Ramesh A.
Kalaany, Nada Y.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (10)
[29] Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation
Salabei, Joshua K.
Lorkiewicz, Pawel K.
Holden, Candice R.
Li, Qianhong
Hong, Kyung U.
Bolli, Roberto
Bhatnagar, Aruni
Hill, Bradford G.
STEM CELLS, 2015, 33 (08) : 2613 - 2627
[30] The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4 (vol 153, pg 840, 2013)
Csibi, Alfred
Fendt, Sarah-Maria
Li, Chenggang
Poulogiannis, George
Choo, Andrew Y.
Chapski, Douglas J.
Jeong, Seung Min
Dempsey, Jamie M.
Parkhitko, Andrey
Morrison, Tasha
Henske, Elizabeth P.
Haigis, Marcia C.
Cantley, Lewis C.
Stephanopoulos, Gregory
Yu, Jane
Blenis, John
CELL, 2021, 184 (08) : 2256 - 2256

← 1 2 3 4 5 →