Genomic characterization and immunotherapy for microsatellite instability-high in cholangiocarcinoma

被引:0
|
作者
Xu Yang
Baofeng Lian
Nan Zhang
Junyu Long
Yiran Li
Jingnan Xue
Xiangqi Chen
Yunchao Wang
Yanyu Wang
Ziyu Xun
Mingjian Piao
Chenpei Zhu
Shanshan Wang
Huishan Sun
Zhijian Song
Leilei Lu
Xiaowei Dong
Aodi Wang
Wenjin Liu
Jie Pan
Xiaorong Hou
Mei Guan
Li Huo
Jie Shi
Haohai Zhang
Jinxue Zhou
Zhenhui Lu
Yilei Mao
Xinting Sang
Liqun Wu
Xiaobo Yang
Kai Wang
Haitao Zhao
机构
[1] Peking Union Medical College Hospital,Department of Liver Surgery, State Key Laboratory of Complex Severe and Rare Diseases
[2] Chinese Academy of Medical Sciences and Peking Union Medical College,Department of Breast Surgery
[3] OrigiMed Co.,Department of Radiology
[4] Ltd,Department of Radiotherapy
[5] Peking,Department of Medical Oncology
[6] Union Medical College Hospital,Department of Nuclear Medicine
[7] Chinese Academy of Medical Sciences & Peking Union Medical College,Department of Pathology
[8] Peking Union Medical College Hospital,Center for Inflammation Research, Department of Anesthesia, Critical Care & Pain Medicine
[9] Chinese Academy of Medical Sciences & Peking Union Medical College,Department of Hepatobiliary and Pancreatic Surgery
[10] Peking Union Medical College Hospital,Hepatobiliary and Pancreatic Surgery
[11] Chinese Academy of Medical Sciences & Peking Union Medical College,Liver Disease Center
[12] Peking Union Medical College Hospital,undefined
[13] Chinese Academy of Medical Sciences & Peking Union Medical College,undefined
[14] Peking Union Medical College Hospital,undefined
[15] Chinese Academy of Medical Sciences & Peking Union Medical College,undefined
[16] Peking Union Medical College Hospital,undefined
[17] Chinese Academy of Medical Sciences & Peking Union Medical College,undefined
[18] Beth Israel Deaconess Medical Center,undefined
[19] Harvard Medical School,undefined
[20] The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital,undefined
[21] Shenzhen Qianhai Shekou Free Trade Zone Hospital,undefined
[22] Affiliated Hospital of Qingdao University,undefined
来源
BMC Medicine | / 22卷
关键词
Microsatellite instability-high; Cholangiocarcinoma; PD-1 inhibitor; PD-L1 expression; Tumor mutation burden; Overall survival; Immune checkpoint inhibitor;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] The degree of microsatellite instability predicts response to PD-1 blockade immunotherapy in mismatch repair-deficient/microsatellite instability-high colorectal cancers
    Wang, Qiao-Xuan
    Qu, Chun-Hua
    Gao, Yuan-Hong
    Ding, Pei-Rong
    Yun, Jing-Ping
    Xie, Dan
    Cai, Mu-Yan
    EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2021, 10 (01)
  • [32] Frequency and characteristic of microsatellite Instability-high cancer in our hospital
    Saito, Akihisa
    Kuraoka, Kazuya
    Ishikawa, Akira
    Zaitsu, Junichi
    Taniyama, Kiyomi
    CANCER SCIENCE, 2021, 112 : 793 - 793
  • [33] Predictive value of microsatellite instability-high remains controversial - Reply
    Boland, C. Richard
    JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (30) : 4857 - 4858
  • [34] Dual checkpoint blockade for microsatellite instability-high colorectal cancer
    Haldar, S. Daniel
    Kopetz, Scott
    LANCET, 2025, 405 (10476):
  • [35] Actionable fusion kinases in microsatellite instability-high colorectal cancers
    Sato, Kazuhito
    Kawazu, Masahito
    Yamamoto, Yoko
    Ueno, Toshihide
    Kojima, Shinya
    Nagae, Genta
    Soda, Manabu
    Oga, Takafumi
    Kohsaka, Shinji
    Sai, Eirin
    Yamashita, Yoshihiro
    Hazama, Shoichi
    Iinuma, Hisae
    Aburatani, Hiroyuki
    Mano, Hiroyuki
    CANCER RESEARCH, 2018, 78 (13)
  • [36] Efficacy and safety of preoperative immunotherapy in patients with mismatch repair-deficient or microsatellite instability-high gastrointestinal malignancies
    Li, Ying-Jie
    Liu, Xin-Zhi
    Yao, Yun-Feng
    Chen, Nan
    Li, Zhong-Wu
    Zhang, Xiao-Yan
    Lin, Xin-Feng
    Wu, Ai-Wen
    WORLD JOURNAL OF GASTROINTESTINAL SURGERY, 2023, 15 (02): : 222 - 233
  • [37] Intrinsic resistance and efficacy of immunotherapy in microsatellite instability-high colorectal cancer: A systematic review and meta-analysis
    Wang, Ren
    Lian, Jie
    Wang, Xin
    Pang, Xiangyi
    Xu, Benjie
    Tang, Shuli
    Shao, Jiayue
    Lu, Haibo
    BIOMOLECULES AND BIOMEDICINE, 2023, 23 (02): : 198 - 208
  • [38] Screening and identification of HLA-A2-restricted neoepitopes for immunotherapy of non-microsatellite instability-high colorectal cancer
    Ranran Shi
    Yubing Li
    Ling Ran
    Yu Dong
    Xiuman Zhou
    Jingwen Tang
    Lu Han
    Mingshuang Wang
    Liwei Pang
    Yuanming Qi
    Yahong Wu
    Yanfeng Gao
    Science China(Life Sciences), 2022, 65 (03) : 572 - 587
  • [39] Comprehensive genetic analysis of microsatellite instability-high colorectal cancers.
    Sato, Kazuhito
    Kawazu, Masahito
    Yamamoto, Yoko
    Mano, Hiroyuki
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [40] Immunotherapy in Localized Microsatellite Instability-High/Mismatch Repair Deficient Solid Tumors: Are We Ready for a New Standard of Care?
    Ciombor, Kristen K.
    Eng, Cathy
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (12) : 2138 - +