Oxygen nanocarrier broke the hypoxia trap of solid tumors and rescued transfection efficiency for gene therapy

被引:0
|
作者
Bing Qin
Mengshi Jiang
Xiang Li
Yingying Shi
Junlei Zhang
Zhenyu Luo
Lihua Luo
Yichao Lu
Xu Liu
Sijie Wang
Yongzhong Du
Yunqing Qiu
Yan Lou
Jian You
机构
[1] Zhejiang University,College of Pharmaceutical Sciences
[2] The First Affiliated Hospital,Zhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research, Department of Clinical Pharmacy
[3] Zhejiang University School of Medicine,undefined
关键词
Hypoxia; PFOB; Oxygen delivery; Gene therapy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [41] Gene therapy in solid tumors: trends in trials in China and beyond
    Chen, Kun
    Wang, Shuhang
    Chen, Bin
    Sun, Fa
    Li, Ning
    DRUG DISCOVERY TODAY, 2021, 26 (02)
  • [42] Hypoxia-responsive synthetic gene circuits to improve safety and potency of CAR T cell therapy for solid tumors.
    Schreiber, Yannick
    Leonard, Joshua
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (23_SUPPL) : 37 - 37
  • [43] Multifunctional Nucleus-targeting Nanoparticles with Ultra-high Gene Transfection Efficiency for In Vivo Gene Therapy
    Li, Ling
    Li, Xia
    Wu, Yuzhe
    Song, Linjiang
    Yang, Xi
    He, Tao
    Wang, Ning
    Yang, Suleixin
    Zeng, Yan
    Wu, Qinjie
    Qian, Zhiyong
    Wei, Yuquan
    Gong, Changyang
    THERANOSTICS, 2017, 7 (06): : 1633 - 1649
  • [44] Nonviral Vectors with a Biosurfactant MEL-A Promote Gene Transfection into Solid Tumors in the Mouse Abdominal Cavity
    Inoh, Yoshikazu
    Furuno, Tadahide
    Hirashima, Naohide
    Nakanishi, Mamoru
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2009, 32 (01) : 126 - 128
  • [45] Dual-targeting nanoparticles with excellent gene transfection efficiency for gene therapy of peritoneal metastasis of colorectal cancer
    Li, Ling
    Deng, Rui
    Su, Yi
    Yang, Cheng
    ONCOTARGET, 2017, 8 (52): : 89837 - 89847
  • [46] EXPERIMENTAL THERAPY FOR SOLID TUMORS BY IN SITU RETROVIRAL MEDIATED GENE TRANSFER
    周中军
    周爱儒
    王建明
    汤健
    牛大地
    林晨
    ChineseJournalofCancerResearch, 1995, (03)
  • [47] The distribution of BRAF gene fusions in solid tumors and response to targeted therapy
    Ross, Jeffrey S.
    Wang, Kai
    Chmielecki, Juliann
    Gay, Laurie
    Johnson, Adrienne
    Chudnovsky, Jacob
    Yelensky, Roman
    Lipson, Doron
    Ali, Siraj M.
    Elvin, Julia A.
    Vergilio, Jo-Anne
    Roels, Steven
    Miller, Vincent A.
    Nakamura, Brooke N.
    Gray, Adam
    Wong, Michael K.
    Stephens, Philip J.
    INTERNATIONAL JOURNAL OF CANCER, 2016, 138 (04) : 881 - 890
  • [48] Transfection of transitional cell carcinoma by extracorporeal acoustical energy: A new method for gene therapy of localized bladder tumors?
    Schaaf, A
    Koehrmann, KU
    Siegsmund, M
    Alken, P
    Michel, S
    JOURNAL OF UROLOGY, 2002, 167 (04): : 114 - 114
  • [49] Transfection of transitional cell carcinoma by extracorporeal acoustcal energy: A new method for gene therapy of localized bladder tumors?
    Schaaf, A
    Sagi, S
    Siegsmund, M
    Alken, P
    Michel, MS
    MOLECULAR THERAPY, 2003, 7 (05) : S382 - S383
  • [50] Use of a stress-inducible promoter in gene therapy of solid tumors.
    Lee, AS
    Chen, X
    Bading, J
    Gambhir, S
    Gomer, C
    CLINICAL CANCER RESEARCH, 2001, 7 (11) : 3783S - 3783S