Cloning of a Novel Homeobox (NK-7.1) Containing Gene, DmHboxNK-7.1, from Drosophila melanogaster

被引：0
|
作者：
Yasuhiko Sakoyama
Ikuko Mizuta
Akihiro Fukunaga
Masanobu Michinomae
Phillip R. Smith
机构：
[1] Osaka University Medical School,Department of Genetics
[2] Utano National Hospital,Clinical Research Center
[3] Osaka City University,Department of Nursing, College of Nursing
[4] Konan University,Department of Biology, Faculty of Science
来源：
Biochemical Genetics | 2002年 / 40卷
关键词：
E5; RT-PCR; homeodomain; opa repeat;
D O I：
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学科分类号：
摘要：
We have cloned a novel Drosophila melanogaster homeobox (Hbox) containing gene, NK-7.1 (Dm.HboxNK-7.1), which is located at 88B3 on the chromosome map, and is 1.5 kb downstream of the spn-B gene. The newly identified gene is expressed at high levels in the embryo, is switched off during larval and pupal stages, and is expressed again in the adult. The Hbox is highly similar to NK-1/S59 (Drosophila) and NK-3/bap (Drosophila). The amino acid (aa) identity ratios (%) were 58 between NK-7.1 and NK-1/S59, and between NK-7.1 and NK-3/bap. The other characteristic structures are the presence of homopolymeric aa stretches consisting of Q, N, and E.
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页码：117 / 127
页数：10
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