First-line PD-1/PD-L1 inhibitor plus chemotherapy vs chemotherapy alone for negative or < 1% PD-L1-expressing metastatic non-small-cell lung cancers

被引:0
|
作者
Thierry Landre
Gaetan Des Guetz
Kader Chouahnia
Cherifa Taleb
Alain Vergnenègre
Christos Chouaïd
机构
[1] Hôpital René-Muret,UCOG 93
[2] APHP,Service d’Oncologie Médicale
[3] Centre Hospitalier Delafontaine,Service d’Oncologie Médicale
[4] Hôpital Avicenne,Service d’Oncogériatrie
[5] APHP,Service de Pneumologie
[6] Hôpital René-Muret,undefined
[7] APHP,undefined
[8] Service d’Oncologie Médicale,undefined
[9] Unité d’Oncologie Thoracique,undefined
[10] Centre Hospitalier Intercommunal (CHI) Créteil,undefined
关键词
Non-small-cell lung cancer; PD-L1; Anti-PD-1/PD-L1; Immunotherapy; Meta-analysis; Management; Chemotherapy;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:441 / 448
页数:7
相关论文
共 50 条
  • [31] PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients
    D'Incecco, A.
    Andreozzi, M.
    Ludovini, V.
    Rossi, E.
    Capodanno, A.
    Landi, L.
    Tibaldi, C.
    Minuti, G.
    Salvini, J.
    Coppi, E.
    Chella, A.
    Fontanini, G.
    Filice, M. E.
    Tornillo, L.
    Incensati, R. M.
    Sani, S.
    Crino, L.
    Terracciano, L.
    Cappuzzo, F.
    BRITISH JOURNAL OF CANCER, 2015, 112 (01) : 95 - 102
  • [32] PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients
    A D'Incecco
    M Andreozzi
    V Ludovini
    E Rossi
    A Capodanno
    L Landi
    C Tibaldi
    G Minuti
    J Salvini
    E Coppi
    A Chella
    G Fontanini
    M E Filice
    L Tornillo
    R M Incensati
    S Sani
    L Crinò
    L Terracciano
    F Cappuzzo
    British Journal of Cancer, 2015, 112 : 95 - 102
  • [33] Prognostic Value of the Pretreatment Lung Immune Prognostic Index in Advanced Small Cell Lung Cancer Patients Treated With First-Line PD-1/PD-L1 Inhibitors Plus Chemotherapy
    Li, Lingling
    Pi, Chenghui
    Yan, Xin
    Lu, Jiangyue
    Yang, Xuhui
    Wang, Chunyu
    Li, Xiaoyan
    Zhang, Sujie
    Zhang, Zhibo
    Sun, Yi
    Hu, Yi
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [34] PD-1/PD-L1 Inhibitors Plus Chemotherapy Versus Chemotherapy Alone as First-Line Therapy for Patients With Unfavorable Cancer of Unknown Primary: A Multicenter, Retrospective Cohort Study
    Huang, Riqing
    Li, Haifeng
    Li, Shuo
    Shu, Ditian
    Chen, Rishang
    Zheng, Zhousan
    Gao, Tinghua
    Chen, Meiting
    Hu, Anqi
    Huang, Yunjie
    Zheng, Qiufan
    An, Xin
    Xue, Cong
    Cai, Yuchen
    Shi, Yanxia
    MEDCOMM, 2025, 6 (03):
  • [35] Biomarkers for PD-1/PD-L1 Blockade Therapy in Non-Small-cell Lung Cancer: Is PD-L1 Expression a Good Marker for Patient Selection?
    Chae, Young Kwang
    Pan, Alan
    Davis, Andrew A.
    Raparia, Kirtee
    Mohindra, Nisha A.
    Matsangou, Maria
    Giles, Francis J.
    CLINICAL LUNG CANCER, 2016, 17 (05) : 350 - 361
  • [36] Chemotherapy plus PD-1/PD-L1 inhibitor versus chemotherapy alone in first-line treatment for recurrent or advanced endometrial cancer: A systematic review and meta-analysis of randomized controlled trials
    de Liz, Caio Dabbous
    Maia, Melissa
    Fonseca Alves, Ana Caroline
    Mendes da Silva, Isadora Mamede
    Oliveira, Joao Pedro
    Ferreira de Oliveira, Audrey Cabral
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [37] Regulatory mechanisms of PD-1/PD-L1 in cancers
    Lin, Xin
    Kang, Kuan
    Chen, Pan
    Zeng, Zhaoyang
    Li, Guiyuan
    Xiong, Wei
    Yi, Mei
    Xiang, Bo
    MOLECULAR CANCER, 2024, 23 (01)
  • [38] Targeting PD-1 or PD-L1 in Metastatic Kidney Cancer: Combination Therapy in the First-Line Setting
    Aggen, David H.
    Drake, Charles G.
    Rini, Brian I.
    CLINICAL CANCER RESEARCH, 2020, 26 (09) : 2087 - 2095
  • [39] PD-1/PD-L1 Inhibitors as Monotherapy in the First-Line Treatment of Advanced Non-Small Cell Lung Cancer Patients with High PD-L1 Expression: An Expert Position Statement
    Isla, Dolores
    Sanchez, Alfredo
    Casal, Joaquin
    Cobo, Manuel
    Majem, Margarita
    Reguart, Noemi
    Zugazagoitia, Jon
    Bernabe, Reyes
    JOURNAL OF CLINICAL MEDICINE, 2023, 12 (15)
  • [40] PD-1/PD-L1 inhibitors plus anti-angiogenic agents with or without chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy as second or later-line treatment for patients with advanced non-small cell lung cancer: A real-world retrospective cohort study
    Chen, Shubin
    Wei, Haowen
    Zhao, Wenhua
    Jiang, Wei
    Ning, Ruiling
    Zhou, Shaozhang
    Tan, Liping
    Wang, Huilin
    Su, Cuiyun
    He, Jianbo
    Zeng, Aiping
    Zhao, Yun
    Yu, Qitao
    FRONTIERS IN IMMUNOLOGY, 2022, 13