A broadly neutralizing antibody against SARS-CoV-2 Omicron variant infection exhibiting a novel trimer dimer conformation in spike protein binding

被引：0
|
作者：
Yingdan Wang
Wuqiang Zhan
Jiangyan Liu
Yanqun Wang
Xiang Zhang
Meng Zhang
Lin Han
Yunping Ma
Lu Lu
Yumei Wen
Zhenguo Chen
Jincun Zhao
Fan Wu
Lei Sun
Jinghe Huang
机构：
[1] Fudan University,Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS) and Shanghai Institute of Infectious Disease and Biosecurity, Shanghai Fifth People’s Hospital, Shanghai Public Health Clinical Center, Institutes of Biomedical Sciences, School o
[2] Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital,Shanghai Immune Therapy Institute
[3] the First Affiliated Hospital of Guangzhou Medical University,State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health
[4] Guangzhou Eighth People’s Hospital of Guangzhou Medical University,Institute of Infectious Disease
来源：
Cell Research | 2022年 / 32卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：862 / 865
页数：3
相关论文
共 50 条
  • [21] Antibody Response after SARS-CoV-2 Infection with the Delta and Omicron Variant
    Blaszczuk, Agata
    Michalski, Aleksander
    Sikora, Dominika
    Malm, Maria
    Drop, Bartlomiej
    Polz-Dacewicz, Malgorzata
    VACCINES, 2022, 10 (10)
  • [22] The SARS-CoV-2 spike protein reversibly samples an open-trimer conformation exposing novel epitopes
    Shoemaker, Sophie R.
    Costello, Shawn M.
    Hobbs, Helen T.
    Nguyen, Annalee W.
    Hsieh, Ching-Lin
    Maynard, Jennifer A.
    McLellan, Jason S.
    Pak, John E.
    Marqusee, Susan
    BIOPHYSICAL JOURNAL, 2022, 121 (03) : 29 - 29
  • [23] A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection
    Tai, Wanbo
    Yang, Kai
    Liu, Yubin
    Li, Ruofan
    Feng, Shengyong
    Chai, Benjie
    Zhuang, Xinyu
    Qi, Shaolong
    Shi, Huicheng
    Liu, Zhida
    Lei, Jiaqi
    Ma, Enhao
    Wang, Weixiao
    Tian, Chongyu
    Le, Ting
    Wang, Jinyong
    Chen, Yunfeng
    Tian, Mingyao
    Xiang, Ye
    Yu, Guocan
    Cheng, Gong
    NATURE COMMUNICATIONS, 2023, 14 (01)
  • [24] Broadly neutralizing antibodies against SARS-CoV-2 variants
    Linqi Zhang
    NationalScienceOpen, 2022, 1 (01) : 24 - 31
  • [25] A lung-selective delivery of mRNA encoding broadly neutralizing antibody against SARS-CoV-2 infection
    Wanbo Tai
    Kai Yang
    Yubin Liu
    Ruofan Li
    Shengyong Feng
    Benjie Chai
    Xinyu Zhuang
    Shaolong Qi
    Huicheng Shi
    Zhida Liu
    Jiaqi Lei
    Enhao Ma
    Weixiao Wang
    Chongyu Tian
    Ting Le
    Jinyong Wang
    Yunfeng Chen
    Mingyao Tian
    Ye Xiang
    Guocan Yu
    Gong Cheng
    Nature Communications, 14 (1)
  • [26] Neutralizing antibody responses in patients hospitalized with SARS-CoV-2 Delta or Omicron infection
    Linderman, Susanne L.
    Lai, Lilin
    Gamarra, Estefany L. Bocangel
    Lau, Max S. Y.
    Edupuganti, Srilatha
    Surie, Diya
    Tenforde, Mark W.
    Chappell, James D.
    Mohr, Nicholas M.
    Gibbs, Kevin W.
    Steingrub, Jay S.
    Exline, Matthew C.
    Shapiro, Nathan I.
    Frosch, Anne E.
    Qadir, Nida
    Davis-Gardner, Meredith E.
    McElrath, M. Juliana
    Lauring, Adam S.
    Suthar, Mehul S.
    Patel, Manish M.
    Self, Wesley H.
    Ahmed, Rafi
    JOURNAL OF CLINICAL INVESTIGATION, 2022, 132 (23):
  • [27] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
    Elisabetta Cameroni
    John E. Bowen
    Laura E. Rosen
    Christian Saliba
    Samantha K. Zepeda
    Katja Culap
    Dora Pinto
    Laura A. VanBlargan
    Anna De Marco
    Julia di Iulio
    Fabrizia Zatta
    Hannah Kaiser
    Julia Noack
    Nisar Farhat
    Nadine Czudnochowski
    Colin Havenar-Daughton
    Kaitlin R. Sprouse
    Josh R. Dillen
    Abigail E. Powell
    Alex Chen
    Cyrus Maher
    Li Yin
    David Sun
    Leah Soriaga
    Jessica Bassi
    Chiara Silacci-Fregni
    Claes Gustafsson
    Nicholas M. Franko
    Jenni Logue
    Najeeha Talat Iqbal
    Ignacio Mazzitelli
    Jorge Geffner
    Renata Grifantini
    Helen Chu
    Andrea Gori
    Agostino Riva
    Olivier Giannini
    Alessandro Ceschi
    Paolo Ferrari
    Pietro E. Cippà
    Alessandra Franzetti-Pellanda
    Christian Garzoni
    Peter J. Halfmann
    Yoshihiro Kawaoka
    Christy Hebner
    Lisa A. Purcell
    Luca Piccoli
    Matteo Samuele Pizzuto
    Alexandra C. Walls
    Michael S. Diamond
    Nature, 2022, 602 : 664 - 670
  • [28] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
    Cameroni, Elisabetta
    Bowen, John E.
    Rosen, Laura E.
    Saliba, Christian
    Zepeda, Samantha K.
    Culap, Katja
    Pinto, Dora
    VanBlargan, Laura A.
    De Marco, Anna
    di Iulio, Julia
    Zatta, Fabrizia
    Kaiser, Hannah
    Noack, Julia
    Farhat, Nisar
    Czudnochowski, Nadine
    Havenar-Daughton, Colin
    Sprouse, Kaitlin R.
    Dillen, Josh R.
    Powell, Abigail E.
    Chen, Alex
    Maher, Cyrus
    Yin, Li
    Sun, David
    Soriaga, Leah
    Bassi, Jessica
    Silacci-Fregni, Chiara
    Gustafsson, Claes
    Franko, Nicholas M.
    Logue, Jenni
    Iqbal, Najeeha Talat
    Mazzitelli, Ignacio
    Geffner, Jorge
    Grifantini, Renata
    Chu, Helen
    Gori, Andrea
    Riva, Agostino
    Giannini, Olivier
    Ceschi, Alessandro
    Ferrari, Paolo
    Cippa, Pietro E.
    Franzetti-Pellanda, Alessandra
    Garzoni, Christian
    Halfmann, Peter J.
    Kawaoka, Yoshihiro
    Hebner, Christy
    Purcell, Lisa A.
    Piccoli, Luca
    Pizzuto, Matteo Samuele
    Walls, Alexandra C.
    Diamond, Michael S.
    NATURE, 2022, 602 (7898) : 664 - +
  • [29] In silico design of miniprotein to inhibit SARS-CoV-2 variant Omicron spike protein
    Wu, Jianhua
    Zhang, Hong-Xing
    Zhang, Jilong
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2023, 25 (21) : 14711 - 14725
  • [30] Structural Study of SARS-CoV-2 Antibodies Identifies a Broad-Spectrum Antibody That Neutralizes the Omicron Variant by Disassembling the Spike Trimer
    Zhan, Wuqiang
    Tian, Xiaolong
    Zhang, Xiang
    Xing, Shenghui
    Song, Wenping
    Liu, Qianying
    Hao, Aihua
    Hu, Yuxia
    Zhang, Meng
    Ying, Tianlei
    Chen, Zhenguo
    Lan, Fei
    Sun, Lei
    JOURNAL OF VIROLOGY, 2022, 96 (16)
12345