Inhibition of the hepatic Nlrp3 protects dopaminergic neurons via attenuating systemic inflammation in a MPTP/p mouse model of Parkinson’s disease

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作者
Chen Qiao
Qian Zhang
Qingling Jiang
Ting Zhang
Miaomiao Chen
Yi Fan
Jianhua Ding
Ming Lu
Gang Hu
机构
[1] Nanjing Medical University,Jiangsu Key Laboratory of Neurodegeneration, Department of Pharmacology
[2] Nanjing University of Chinese Medicine,Department of Pharmacology
[3] Nanjing Medical University,Neuroprotective Drug Discovery Key Laboratory, Department of Pharmacology
[4] Affiliated Hospital of Jiangsu University,Department of Clinical Pharmacy
[5] Jiangsu University,undefined
关键词
NLRP3 inflammasome; Systemic inflammation; Neurodegeneration; IL-1β; Parkinson’s disease;
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