Gene therapy for glioblestome multiforme: in vivo tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir

被引:0
|
作者
G. Stockhammer
J. Brotchi
R. Leblanc
M. Bernstein
G. Schackert
F. Weber
C. Ostertag
N. H. Mulder
H. Mellstedt
R. Seiler
Y. Yonekawa
K. Twerdy
H. Kostron
O. De Witte
M. Lambermont
T. Velu
P. Laneuville
J.-G. Villemure
J. T. Rutka
P. Warnke
M. Laseur
J. J. A. Mooij
J. Boëthius
L. Mariani
M. Meyer
C. Brändli
K. Frei
D. Könu
A. Gianella-Borradori
机构
[1] Sandoz Pharma,
[2] Ltd.,undefined
[3] CH-4002 Basel,undefined
[4] Switzerland,undefined
[5] University of Innsbruck,undefined
[6] Innsbruck,undefined
[7] Austria,undefined
[8] Hôpital Erasme,undefined
[9] Brussels,undefined
[10] Belgium,undefined
[11] Montreal Neurological Institute,undefined
[12] Montreal,undefined
[13] Quebec,undefined
[14] Canada,undefined
[15] Royal Victoria Hospital,undefined
[16] Montreal,undefined
[17] Quebec,undefined
[18] Canada,undefined
[19] Toronto Hospital,undefined
[20] Toronto,undefined
[21] Ontario,undefined
[22] Canada,undefined
[23] Hospital for Sick Children,undefined
[24] Toronto,undefined
[25] Ontario,undefined
[26] Canada,undefined
[27] Universitätsklinikum Karl Gustav Carus,undefined
[28] Dresden,undefined
[29] Germany,undefined
[30] Universitätsklinikum,undefined
[31] Düsseldorf,undefined
[32] Germany,undefined
[33] Neurozentrum Freiburg,undefined
[34] Freiburg,undefined
[35] Germany,undefined
[36] University Hospital Groningen,undefined
[37] Groningen,undefined
[38] The Netherlands,undefined
[39] Karolinska Hospital,undefined
[40] Stockholm,undefined
[41] Sweden,undefined
[42] Inselspital,undefined
[43] Bern,undefined
[44] Switzerland,undefined
[45] Universitätsspital,undefined
[46] Zürich,undefined
[47] Switzerland,undefined
来源
关键词
Gene Therapy; Thymidine; Herpes Simplex; Ganciclovir; Thymidine Kinase;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:300 / 304
页数:4
相关论文
共 50 条
  • [21] In vivo gene therapy of ovarian cancer by adenovirus-mediated thymidine kinase gene transduction and ganciclovir administration
    Tong, XW
    Block, A
    Chen, SH
    Contant, CF
    Agoulnik, I
    Blankenburg, K
    Kaufman, RH
    Woo, SLC
    Kieback, DG
    GYNECOLOGIC ONCOLOGY, 1996, 61 (02) : 175 - 179
  • [22] Limited efficacy of gene transfer in herpes simplex virus-thymidine kinase/ganciclovir gene therapy for brain tumors
    Hadaczek, P
    Mirek, H
    Berger, MS
    Bankiewicz, K
    JOURNAL OF NEUROSURGERY, 2005, 102 (02) : 328 - 335
  • [23] Retinoids augment the bystander effect in vitro and in vivo in herpes simplex virus thymidine kinase ganciclovir-mediated gene therapy
    Park, JY
    Elshami, AA
    Amin, K
    Rizk, N
    Kaiser, LR
    Albelda, SM
    GENE THERAPY, 1997, 4 (09) : 909 - 917
  • [24] Retinoids augment the bystander effect in vitro and in vivo in herpes simplex virus thymidine kinase/ganciclovir-mediated gene therapy
    JY Park
    AA Elshami
    K Amin
    N Rizk
    LR Kaiser
    SM Albelda
    Gene Therapy, 1997, 4 : 909 - 917
  • [25] Multitracer studies during gene therapy of hepatoma cells with herpes simplex virus thymidine kinase and ganciclovir
    Haberkorn, U
    Altmann, A
    Morr, I
    Germann, C
    Oberdorfer, F
    vanKaick, G
    JOURNAL OF NUCLEAR MEDICINE, 1997, 38 (07) : 1048 - 1054
  • [26] Osteosarcoma and chondrosarcoma as targets for virus vectors and herpes simplex virus thymidine kinase/ganciclovir gene therapy
    Ketola, A
    Määttä, AM
    Pasanen, T
    Tulimäki, K
    Wahlfors, J
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2004, 13 (05) : 705 - 710
  • [27] Herpes simplex virus thymidine kinase gene/ganciclovir gene therapy for primary malignant glioma: Results of a phase III study
    Rainov, NG
    CANCER GENE THERAPY, 2000, 7 (08) : 1208 - 1208
  • [28] Anti-tumor natural killer cells are induced by herpes simplex virus thymidine kinase gene transduction and ganciclovir therapy in a mouse model of prostate cancer.
    Atkinson, G
    Sanford, MA
    Zaslau, S
    Chen, SH
    Hall, SJ
    JOURNAL OF UROLOGY, 1998, 159 (05): : 8 - 8
  • [29] A phase I trial of in vivo gene therapy with the herpes simplex thymidine kinase ganciclovir system for the treatment of refractory or recurrent ovarian cancer
    Link, CJ
    Moorman, D
    Seregina, T
    Levy, JP
    Schabold, KJ
    HUMAN GENE THERAPY, 1996, 7 (09) : 1161 - 1179
  • [30] Immunotherapy of murine prostate cancer using whole tumor cells killed ex vivo by herpes simplex viral thymidine kinase/ganciclovir suicide gene therapy
    Pandha, H
    Eaton, J
    Greenhalgh, R
    Soars, D
    Dalgleish, A
    CANCER GENE THERAPY, 2005, 12 (06) : 572 - 578