Gene therapy for glioblestome multiforme: in vivo tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir

被引：0

作者：

G. Stockhammer

J. Brotchi

R. Leblanc

M. Bernstein

G. Schackert

F. Weber

C. Ostertag

N. H. Mulder

H. Mellstedt

R. Seiler

Y. Yonekawa

K. Twerdy

H. Kostron

O. De Witte

M. Lambermont

T. Velu

P. Laneuville

J.-G. Villemure

J. T. Rutka

P. Warnke

M. Laseur

J. J. A. Mooij

J. Boëthius

L. Mariani

M. Meyer

C. Brändli

K. Frei

D. Könu

A. Gianella-Borradori

机构：

[1] Sandoz Pharma,

[2] Ltd.,undefined

[3] CH-4002 Basel,undefined

[4] Switzerland,undefined

[5] University of Innsbruck,undefined

[6] Innsbruck,undefined

[7] Austria,undefined

[8] Hôpital Erasme,undefined

[9] Brussels,undefined

[10] Belgium,undefined

[11] Montreal Neurological Institute,undefined

[12] Montreal,undefined

[13] Quebec,undefined

[14] Canada,undefined

[15] Royal Victoria Hospital,undefined

[16] Montreal,undefined

[17] Quebec,undefined

[18] Canada,undefined

[19] Toronto Hospital,undefined

[20] Toronto,undefined

[21] Ontario,undefined

[22] Canada,undefined

[23] Hospital for Sick Children,undefined

[24] Toronto,undefined

[25] Ontario,undefined

[26] Canada,undefined

[27] Universitätsklinikum Karl Gustav Carus,undefined

[28] Dresden,undefined

[29] Germany,undefined

[30] Universitätsklinikum,undefined

[31] Düsseldorf,undefined

[32] Germany,undefined

[33] Neurozentrum Freiburg,undefined

[34] Freiburg,undefined

[35] Germany,undefined

[36] University Hospital Groningen,undefined

[37] Groningen,undefined

[38] The Netherlands,undefined

[39] Karolinska Hospital,undefined

[40] Stockholm,undefined

[41] Sweden,undefined

[42] Inselspital,undefined

[43] Bern,undefined

[44] Switzerland,undefined

[45] Universitätsspital,undefined

[46] Zürich,undefined

[47] Switzerland,undefined

来源：

Journal of Molecular Medicine | 1997年 / 75卷

关键词：

Gene Therapy; Thymidine; Herpes Simplex; Ganciclovir; Thymidine Kinase;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：300 / 304

页数：4

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[1] Gene therapy for glioblestome multiforme: In vivo tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
Stockhammer, G
Brotchi, J
Leblanc, R
Bernstein, M
Schackert, G
Weber, F
Ostertag, C
Mulder, NH
Mellstedt, H
Seiler, R
Yonekawa, Y
Twerdy, K
Kostron, H
DeWitte, O
Lambermont, M
Velu, T
Laneuville, P
Villemure, JG
Rutka, JT
Warnke, P
Laseur, M
Mooij, JJA
Boethius, J
Mariani, L
Meyer, M
Brandli, C
Frei, K
Konu, D
GianellaBorradori, A
JOURNAL OF MOLECULAR MEDICINE-JMM, 1997, 75 (04): : 300 - 304
[2] A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir
Shand, N
Weber, F
Mariani, L
Bernstein, M
Gianella-Borradori, A
Long, Z
Sorensen, AG
Barbier, N
HUMAN GENE THERAPY, 1999, 10 (14) : 2325 - 2335
[3] Liposomal gene therapy with the herpes simplex thymidine kinase gene/ganciclovir system for the treatment of glioblastoma multiforme
Voges, J
Weber, F
Reszka, R
Sturm, V
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Heiss, WD
Wiestler, O
Kapp, JF
HUMAN GENE THERAPY, 2002, 13 (05) : 675 - 685
[4] Prostate cancer gene therapy: Herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models
Eastham, JA
Chen, SH
Sehgal, I
Yang, G
Timme, TL
Hall, SJ
Woo, SLC
Thompson, TC
HUMAN GENE THERAPY, 1996, 7 (04) : 515 - 523
[5] GENE-THERAPY FOR THE TREATMENT OF MALIGNANT BRAIN-TUMORS WITH IN-VIVO TUMOR TRANSDUCTION WITH THE HERPES-SIMPLEX THYMIDINE KINASE GENE GANCICLOVIR SYSTEM
CULVER, KW
VANGILDER, J
LINK, CJ
CARLSTROM, T
BUROKER, T
YUH, W
KOCH, K
SCHABOLD, K
DOORNBAS, S
WETJEN, B
BLAESE, RM
HUMAN GENE THERAPY, 1994, 5 (03) : 343 - 379
[6] GENE-THERAPY FOR THE TREATMENT OF RECURRENT PEDIATRIC MALIGNANT ASTROCYTOMAS WITH IN-VIVO TUMOR TRANSDUCTION WITH THE HERPES-SIMPLEX THYMIDINE KINASE GENE GANCICLOVIR SYSTEM
RAFFEL, C
CULVER, K
KOHN, D
NELSON, M
SIEGEL, S
GILLIS, F
LINK, CJ
VILLABLANCA, JG
ANDERSON, WF
HUMAN GENE THERAPY, 1994, 5 (07) : 863 - 890
[7] Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy
PD Boucher
LJ Ostruszka
PJM Murphy
DS Shewach
Gene Therapy, 2002, 9 : 1023 - 1030
[8] Hydroxyurea significantly enhances tumor growth delay in vivo with herpes simplex virus thymidine kinase/ganciclovir gene therapy
Boucher, PD
Ostruszka, LJ
Murphy, PJM
Shewach, DS
GENE THERAPY, 2002, 9 (15) : 1023 - 1030
[9] Human malignant brain tumor response to herpes simplex thymidine kinase (HSVtk)/ganciclovir gene therapy
Izquierdo, M
Martin, V
deFelipe, P
Izquierdo, JM
PerezHigueras, A
Cortes, ML
Paz, JF
Isla, A
Blazquez, MG
GENE THERAPY, 1996, 3 (06) : 491 - 495
[10] Gene therapy for retinoblastoma: Comparison of gene replacement with the retinoblastoma gene to suicide gene therapy with herpes simplex thymidine kinase and ganciclovir
Hurwitz, RL
Rivera, AL
Holcombe, VN
Chevez-Barrios, P
Hurwitz, MY
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1999, 40 (04) : S761 - S761

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