An overview of the structures of protein-DNA complexes

被引：0
|
作者：
Nicholas M Luscombe
Susan E Austin
Helen M Berman
Janet M Thornton
机构：
[1] University College,Biomolecular Structure and Modelling Unit, Department of Biochemistry and Molecular Biology
[2] Rutgers State University,Department of Chemistry
[3] Birkbeck College,Department of Crystallography
来源：
Genome Biology | / 1卷 / 1期
关键词：
Protein Data Bank; Minor Groove; Major Groove; Protein Data Bank Entry; Integration Host Factor;
D O I：
10.1186/gb-2000-1-1-reviews001
中图分类号：
学科分类号：
摘要：
On the basis of a structural analysis of 240 protein-DNA complexes contained in the Protein Data Bank (PDB), we have classified the DNA-binding proteins involved into eight different structural/functional groups, which are further classified into 54 structural families. Here we present this classification and review the functions, structures and binding interactions of these protein-DNA complexes.
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