Host immune defence, amyloid-β peptide and Alzheimer disease

被引:0
|
作者
Todd E. Golde
机构
[1] Center for Translational Research in Neurodegenerative Disease,Department of Neuroscience
[2] McKnight Brian Institute,undefined
[3] College of Medicine,undefined
[4] University of Florida,undefined
来源
Nature Reviews Neurology | 2016年 / 12卷
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摘要
A recent study demonstrates that amyloid-β (Aβ) can function as an antimicrobial peptide, and additional data show that bacteria and yeast can seed Aβ deposition into amyloid. These data suggest a complex interplay between the normal function of Aβ, its accumulation in the brain, and host immune defence.
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页码:433 / 434
页数:1
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