Robo is Abl to block N-Cadherin function

被引:0
|
作者
Mark M. Emerson
David Van Vactor
机构
[1] the Deptartment of Cell Biology and Program in Neuroscience at Harvard Medical School,
来源
Nature Cell Biology | 2002年 / 4卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The molecular pathways involved in wiring the brain have just begun to be elucidated. Work in this issue of Nature Cell Biology has uncovered inhibitory interactions between two such pathways: Roundabout (Robo) and N-Cadherin. This discovery provides a potential mechanistic understanding of how pathways are used in a coordinated manner to guide axons.
引用
收藏
页码:E227 / E229
相关论文
共 50 条
  • [21] Discovery and development of N-cadherin antagonists
    Blaschuk, Orest W.
    CELL AND TISSUE RESEARCH, 2012, 348 (02) : 309 - 313
  • [22] Discovery and development of N-cadherin antagonists
    Orest W. Blaschuk
    Cell and Tissue Research, 2012, 348 : 309 - 313
  • [23] N-cadherin at the glial scar in the rat
    Vázquez-Chona, F
    Geisert, EE
    BRAIN RESEARCH, 1999, 838 (1-2) : 45 - 50
  • [24] Role of N-cadherin in bone formation
    Marie, PJ
    JOURNAL OF CELLULAR PHYSIOLOGY, 2002, 190 (03) : 297 - 305
  • [25] N-cadherin antagonists as oncology therapeutics
    Blaschuk, Orest W.
    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2015, 370 (1661)
  • [26] Identification of novel N-cadherin antagonist
    Devemy, Emmanuelle
    Blaschuk, Orest W.
    PEPTIDES, 2008, 29 (11) : 1853 - 1861
  • [27] GUIDANCE OF OPTIC AXONS BY N-CADHERIN
    MATSUNAGA, M
    HATTA, K
    NAGAFUCHI, A
    TAKEICHI, M
    DEVELOPMENT GROWTH & DIFFERENTIATION, 1988, 30 (04) : 424 - 424
  • [28] N-Cadherin Juxtacrine Signaling Maintains Blood Brain Barrier and Cognitive Function
    Lee, Quinn S.
    Kruse, Kevin N.
    Marottoli, Felecia M.
    Thomas, Riya
    Sun, Ying
    Tai, Leon M.
    Komarova, Yulia A.
    FASEB JOURNAL, 2018, 32 (01):
  • [29] Spatiotemporal Distribution and Function of N-Cadherin in Postnatal Schwann Cells: A Matter of Adhesion?
    Core, Mikael
    Wicher, Grzegorz
    Limbach, Christoph
    Kilimann, Manfred W.
    Colman, David R.
    Svenningsen, Asa Fex
    JOURNAL OF NEUROSCIENCE RESEARCH, 2010, 88 (11) : 2338 - 2349
  • [30] Regulation and function of N-cadherin post-translational cleavage in glioblastoma cells
    Kohutek, Zachary
    Hussaini, Isa
    NEURO-ONCOLOGY, 2007, 9 (04) : 472 - 472