Robo is Abl to block N-Cadherin function

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作者
Mark M. Emerson
David Van Vactor
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[1] the Deptartment of Cell Biology and Program in Neuroscience at Harvard Medical School,
来源
Nature Cell Biology | 2002年 / 4卷
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摘要
The molecular pathways involved in wiring the brain have just begun to be elucidated. Work in this issue of Nature Cell Biology has uncovered inhibitory interactions between two such pathways: Roundabout (Robo) and N-Cadherin. This discovery provides a potential mechanistic understanding of how pathways are used in a coordinated manner to guide axons.
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页码:E227 / E229
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