Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions

被引：0
|
作者：
Hannah Britz
Nina Hanke
Mitchell E. Taub
Ting Wang
Bhagwat Prasad
Éric Fernandez
Peter Stopfer
Valerie Nock
Thorsten Lehr
机构：
[1] Saarland University,Clinical Pharmacy
[2] Drug Metabolism and Pharmacokinetics,Department of Pharmaceutical Sciences
[3] Boehringer Ingelheim Pharmaceuticals Inc.,undefined
[4] Washington State University,undefined
[5] Translational Medicine and Clinical Pharmacology,undefined
[6] Boehringer Ingelheim Pharma GmbH & Co. KG,undefined
来源：
Pharmaceutical Research | 2020年 / 37卷
关键词：
drug-drug interaction (DDI); furosemide; organic anion transporter (OAT); physiologically based pharmacokinetic modeling (PBPK); probenecid;
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