Leaf Extract from European Olive (Olea europaea L.) Post-Transcriptionally Suppresses the Epithelial-Mesenchymal Transition and Sensitizes Gastric Cancer Cells to Chemotherapy

被引:0
|
作者
Cagla Tekin
Melis Ercelik
Pavel Dunaev
Aigul Galembikova
Gulcin Tezcan
Secil Ak Aksoy
Ferah Budak
Ozgen Isık
Nesrin Ugras
Sergei Boichuk
Berrin Tunca
机构
[1] Bursa Uludag University,Department of Medical Biology, Faculty of Medicine
[2] Kazan State Medical University,Department of Pathology
[3] Bursa Uludag University,Department of Fundamental Sciences, Faculty of Dentistry
[4] Bursa Uludag University,Inegol Vocation School
[5] Bursa Uludag University,Experimental Animal Breeding and Research Unit, Faculty of Medicine
[6] Bursa Uludag University,Department of Immunology, Medical Faculty
[7] Bursa Uludag University,Department of General Surgery, Medical Faculty
[8] Bursa Uludag University,Department of Pathology, Medical Faculty
[9] Russian Medical Academy of Continuous Professional Education,Department of Radiotherapy and Radiology
[10] Kazan Federal University,“Biomarker” Research Laboratory, Institute of Fundamental Medicine and Biology
来源
Biochemistry (Moscow) | 2024年 / 89卷
关键词
gastric cancer; leaf extract; epithelial-mesenchymal transition; apoptosis; chemotherapeutic agents; cadherin 2; SOX2; non-coding RNA; miR-23b-3p; anti-cancer effect;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:97 / 115
页数:18
相关论文
共 32 条
  • [11] Anti-adhesion activity of thyme (Thymus vulgaris L.) extract, thyme post-distillation waste, and olive (Olea europea L.) leaf extract against Campylobacter jejuni on polystyrene and intestine epithelial cells
    Pogacar, Maja Sikic
    Klancnik, Anja
    Bucar, Franz
    Langerholc, Tomaz
    Mozina, Sonja Smole
    JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2016, 96 (08) : 2723 - 2730
  • [12] Jorunnamycin A from Xestospongia sp. Suppresses Epithelial to Mesenchymal Transition and Sensitizes Anoikis in Human Lung Cancer Cells
    Ecoy, Gea Abigail Uy
    Chamni, Supakarn
    Suwanborirux, Khanit
    Chanvorachote, Pithi
    Chaotham, Chatchai
    JOURNAL OF NATURAL PRODUCTS, 2019, 82 (07): : 1861 - 1873
  • [13] Epithelial-mesenchymal transition contributes to malignant phenotypes of circulating tumor cells derived from gastric cancer
    Wu, Tiangen
    Bao, Tianhao
    Liang, Daoming
    Wang, Lin
    BIOCELL, 2019, 43 (04) : 293 - 298
  • [14] Trefoil Factor 1 Suppresses Epithelial-mesenchymal Transition through Inhibition of TGF-beta Signaling in Gastric Cancer Cells
    Lee, Da-Young
    Song, Moon-Young
    Kim, Eun-Hee
    JOURNAL OF CANCER PREVENTION, 2021, 26 (02) : 137 - 144
  • [15] Extract from Moringa oleifera seeds suppresses the epithelial-mesenchymal transition-mediated metastasis of gastric cancer by targeting the metastatic suppressor NDRG1
    Shu, Xing-sheng
    Wang, Dan-dan
    Zhao, Ying-ying
    Sun, Yan-mei
    Hu, Xiao-peng
    Huang, Xiao-yan
    Zeng, Jun-hui
    Li, Chen-yang
    Li, Yan
    Zeng, Yong
    Wang, Xiao-mei
    He, Zhen-dan
    Ying, Ying
    JOURNAL OF FUNCTIONAL FOODS, 2018, 50 : 93 - 103
  • [16] Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states
    Yoshida, T.
    Ozawa, Y.
    Kimura, T.
    Sato, Y.
    Kuznetsov, G.
    Xu, S.
    Uesugi, M.
    Agoulnik, S.
    Taylor, N.
    Funahashi, Y.
    Matsui, J.
    BRITISH JOURNAL OF CANCER, 2014, 110 (06) : 1497 - 1505
  • [17] Differential Radiomodulating Action of Olea europaea L. cv. Caiazzana Leaf Extract on Human Normal and Cancer Cells: A Joint Chemical and Radiobiological Approach
    Pacifico, Severina
    Blaha, Pavel
    Faramarzi, Shadab
    Fede, Francesca
    Michalickova, Katarina
    Piccolella, Simona
    Ricciardi, Valerio
    Manti, Lorenzo
    ANTIOXIDANTS, 2022, 11 (08)
  • [18] Melittin suppresses epithelial-mesenchymal transition and metastasis in human gastric cancer AGS cells via regulating Wnt/BMP associated pathway
    Huang, Jye-Yu
    Peng, Shu-Fen
    Chueh, Fu-Shin
    Chen, Po-Yuan
    Huang, Yi-Ping
    Huang, Wen-Wen
    Chung, Jing-Gung
    BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2021, 85 (11) : 2250 - 2262
  • [19] Celastrus orbiculatus extract suppresses the epithelial-mesenchymal transition by mediating cytoskeleton rearrangement via inhibition of the Cofilin 1 signaling pathway in human gastric cancer
    Wang, Haibo
    Gui, Hao
    Feng, Jun
    Qian, Yayun
    Yang, Lin
    Jin, Eng
    Wang, Xuanyi
    Chen, Jue
    Shi, Youyang
    Lu, Songhua
    Zhao, Min
    Liu, Yanqing
    ONCOLOGY LETTERS, 2017, 14 (03) : 2926 - 2932
  • [20] MiR-520d-3p suppresses the proliferation and epithelial-mesenchymal transition of cervical cancer cells by targeting ZFP36L2
    Zhang, Yuan
    Tian, Fei
    Zhao, Jing
    HELIYON, 2023, 9 (08)