Bringing the genomic landscape of small-cell lung cancer into focus

被引：0

作者：

M Catherine Pietanza

Marc Ladanyi

机构：

[1] New York,M. Catherine Pietanza is in the Department of Medicine (Thoracic Oncology Service) Memorial Sloan

[2] New York,Kettering Cancer Center

[3] USA.,Marc Ladanyi is in the Department of Pathology and the Human Oncology and Pathogenesis Program at the Memorial Sloan

[4] New York,Kettering Cancer Center

[5] New York,undefined

[6] USA.,undefined

来源：

Nature Genetics | 2012年 / 44卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

Genomic characterization efforts in small-cell lung cancer have been complicated by the paucity of high-quality surgical resection specimens for this aggressive lung cancer subtype that is usually diagnosed at unresectable stages in small biopsies or cytology specimens. Now, two papers report genomic analyses of small-cell lung cancer, highlighting subsets of tumors driven by amplification of FGFR1, SOX2 or MYC family members or by a MYCL1 fusion oncogene, among many other recurrent alterations.

引用

页码：1074 / 1075

页数：1

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