Metabolic fate of 14C-labelled chlorinated and non-chlorinated fatty acids in goldfish (Carassius auratus)

被引：0

作者：

H. Björn

G. Ewald

P. Sundin

C. Wesén

J. Skramstad

P. Frøyen

机构：

[1] Lund University,Chemical Ecology and Ecotoxicology, Department of Ecology, Ecology Building

[2] Lund University,Department of Chemical Engineering

[3] Swedish University of Agricultural Sciences,Department of Environmental Assessment

[4] Lund University,Department of Technical Analytical Chemistry, Center for Chemistry and Chemical Engineering

[5] University of Oslo,Department of Chemistry

来源：

Fish Physiology and Biochemistry | 2004年 / 30卷

关键词：

chlorinated fatty acids; fatty acid turnover; lipid metabolism; respiration;

D O I：

暂无

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学科分类号：

摘要：

In order to study the metabolic fate of chlorinated fatty acids in fish, goldfish were fed either 9,10-dichlorostearic acid or oleic acid, chosen as the unchlorinated analogue, both radiolabelled at either the carboxyl (1st) or the terminal (18th) carbon of the fatty acid chain. By keeping the fish in hermetically closed aquaria, all the respired, assimilated and excreted radioactivity could be accounted for. Fish fed 9,10-dichlorostearic acid labelled in the terminal end respired radioactive CO2 to a much lower degree than fish fed the other test compounds. As a consequence, the radioactivity bound in lipids was higher in the group of fish fed dichlorostearic acid labelled in the terminal end. It is suggested that the chlorine atoms in the middle of the carbon chain obstruct the metabolic turn-over of 9,10-dichlorostearic acid, which may have an impact on the residence time of these compounds in the ecosystem.

引用

页码：13 / 20

页数：7