L(ou)sy miRNA targets?

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作者
Nikolaus Rajewsky
机构
[1] the Max Delbrück Centrum für Molekulare Medizin,
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摘要
MicroRNAs (miRNAs) are noncoding small RNAs thought to post-transcriptionally regulate many metazoan genes by binding to partially complementary sites in target messenger RNAs. In this issue, Didiano and Hobert examine known and predicted targets of the nematode lsy-6 miRNA, question the general validity of previously proposed rules about miRNA-target interactions and suggest that many functional miRNA targets might be context dependent, as seen in metazoan gene regulation by transcription factors.
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页码:754 / 755
页数:1
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