Cryo-EM, XFELs and the structure conundrum in structural biology

被引:0
|
作者
Abbas Ourmazd
机构
[1] University of Wisconsin Milwaukee,Department of Physics
来源
Nature Methods | 2019年 / 16卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Single-particle techniques offer an unprecedented opportunity to understand the role of structural variability in biological function. They also call into question the meaning of ‘a structure’ and its relevance to function.
引用
收藏
页码:941 / 944
页数:3
相关论文
共 50 条
  • [11] Cryo-EM: A new dawn in thyroid biology
    Coscia, Francesca
    Taler-Vercic, Ajda
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2021, 531
  • [12] Introduction: Cryo-EM in Biology and Materials Research
    Subramaniam, Sriram
    Danino, Dganit
    CHEMICAL REVIEWS, 2022, 122 (17) : 13881 - 13882
  • [13] The big picture of chromatin biology by cryo-EM
    Jang, Seongmin
    Song, Ji-Joon
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 2019, 58 : 76 - 87
  • [14] Structural ensemble refinement with cryo-EM
    Tang, Wai Shing
    Silva, David
    Barreto, Julian Giraldo
    Thiede, Erik H.
    Hanson, Sonya M.
    Cossio, Pilar
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 542A - 542A
  • [15] Improving cryo-EM structure validation
    Alexis Rohou
    Nature Methods, 2021, 18 : 130 - 131
  • [16] Cryo-EM structure of the SEA complex
    Lucas Tafur
    Kerstin Hinterndorfer
    Caroline Gabus
    Chiara Lamanna
    Ariane Bergmann
    Yashar Sadian
    Farzad Hamdi
    Fotis L. Kyrilis
    Panagiotis L. Kastritis
    Robbie Loewith
    Nature, 2022, 611 : 399 - 404
  • [17] Cryo-EM Structure of a Possum Enterovirus
    Wang, Ivy
    Gupta, Sandeep K.
    Ems, Guillaume
    Jayawardena, Nadishka
    Strauss, Mike
    Bostina, Mihnea
    VIRUSES-BASEL, 2022, 14 (02):
  • [18] Cryo-EM structure of a transcribing cypovirus
    Yang, Chongwen
    Jia, Gang
    Liu, Hongrong
    Zhang, Kai
    Liu, Guangqiao
    Sun, Fei
    Zhu, Ping
    Cheng, Lingpeng
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 109 (16) : 6118 - 6123
  • [19] THE CRYO-EM STRUCTURE OF ZIKA VIRUS
    Sirohi, Devika
    Chen, Zhenguo
    Sun, Lei
    Klose, Thomas
    Pierson, Theodore C.
    Rossmann, Michael G.
    Kuhn, Richard J.
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 95 (05): : 571 - 571
  • [20] Cryo-EM structure of the SEA complex
    Tafur, Lucas
    Hinterndorfer, Kerstin
    Gabus, Caroline
    Lamanna, Chiara
    Bergmann, Ariane
    Sadian, Yashar
    Hamdi, Farzad
    Kyrilis, Fotis L.
    Kastritis, Panagiotis L.
    Loewith, Robbie
    NATURE, 2022, 611 (7935) : 399 - +