Synthesis and Anthelmintic and Insecticidal Activities of 1-R-3-Methyl-6-Methoxy-7-( P-Propoxy)-3,4-Dihydroisoquinoline Hydrochlorides

被引：0

作者：

O. V. Surikova

A. G. Mikhailovskii

B. Ya. Syropyatov

A. S. Yusov

机构：

[1] Perm State Pharmaceutical Academy,

来源：

Pharmaceutical Chemistry Journal | 2017年 / 50卷

关键词：

cyclocondensation of ; -; -propyleugenol with nitriles; 1-; -3-methyl-6-methoxy-7-(; -propoxy)-3,4-dihydroisoquinoline hydrochlorides; anthelmintic and insecticidal activity;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

1-R-3-Methyl-6-methoxy-7-(n-propoxy)-3,4-dihydroisoquinolines were synthesized via cyclocondensation of O-n-propyleugenol with various nitriles. It was shown that the hydrochlorides of the synthesized compounds exhibited anthelmintic and weak insecticidal activity. The isoquinoline containing a 1-benzyl radical had the greatest anthelmintic activity and was more potent than pyrantel and imidacloprid.

引用

页码：794 / 797

页数：3

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