Expression of the placenta-specific, 100 kDa ras GTPase activating protein in several human cancer cell lines and normal human tissues

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作者
Yuzuru Araki
Kazuhiko Nakamura
Yoshiharu Chijiiwa
Hajime Nawata
机构
[1] Kyushu University,Third Department of Internal Medicine, Faculty of Medicine
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ras GTPase activating protein (ras GAP); colon cancer;
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摘要
The ras GTPase activating protein (ras GAP), a regulator of Ras activity, has two isoforms; ras GAP 120 and ras GAP 100. The latter, whose molecular size is about 100 kDa, is generated alternative splicing from the ras GAP 120 gene and is considered placenta-specific, while the former is expressed ubiquitously.
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页码:195 / 204
页数:9
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