NRP1 inhibition modulates radiosensitivity of medulloblastoma by targeting cancer stem cells

被引：0
|
作者：
Manon Douyère
Caifeng Gong
Mylène Richard
Nadia Pellegrini-Moïse
Joël Daouk
Julien Pierson
Pascal Chastagner
Cédric Boura
机构：
[1] Université de Lorraine,Department of Medical Oncology
[2] CNRS,undefined
[3] CRAN,undefined
[4] UMR 7039,undefined
[5] National Cancer Center/National Clinical Research Center for Can-Cer/Cancer Hospital,undefined
[6] Chinese Academy of Medical Sciences and Peking Union Medical College,undefined
[7] Université de Lorraine,undefined
[8] CNRS,undefined
[9] L2CM,undefined
[10] UMR 7053,undefined
[11] Service d’Onco-Hématologie Pédiatrique,undefined
[12] CHRU-Nancy,undefined
来源：
Cancer Cell International | / 22卷
关键词：
Medulloblastoma; Neuropilin-1; Cancer stem cells; Radiotherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [41] Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch
    Irene Maria Aspalter
    Emma Gordon
    Alexandre Dubrac
    Anan Ragab
    Jarek Narloch
    Pedro Vizán
    Ilse Geudens
    Russell Thomas Collins
    Claudio Areias Franco
    Cristina Luna Abrahams
    Gavin Thurston
    Marcus Fruttiger
    Ian Rosewell
    Anne Eichmann
    Holger Gerhardt
    Nature Communications, 6
  • [42] Insilico targeting of virus entry facilitator NRP1 to block SARS-CoV2 entry
    Bibi, Nousheen
    Shah, Maleeha
    Khan, Shahzad
    Chohan, Muhammad Shahzad
    Kamal, Mohammad Amjad
    PLOS ONE, 2025, 20 (02):
  • [43] Discovery of novel PARP1/NRP1 dual-targeting inhibitors with strong antitumor potency
    Liu, Juanjuan
    Geng, Yifei
    Jiang, Su
    Guan, Lixia
    Gao, Junyi
    Niu, Miao-Miao
    Li, Jindong
    FRONTIERS IN PHARMACOLOGY, 2024, 15
  • [44] hsa-miR-212 modulates the radiosensitivity of glioma cells by targeting BRCA1
    He, Xin
    Fan, Saijun
    ONCOLOGY REPORTS, 2018, 39 (03) : 977 - 984
  • [45] STAT6 Upregulates NRP1 Expression in Endothelial Cells and Promotes Angiogenesis
    Gao, Peng
    Ren, Guanghui
    Liang, Jiangjiu
    Liu, Ju
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [46] Trafficking dynamics of VEGFR1, VEGFR2, and NRP1 in human endothelial cells
    Sarabipour, Sarvenaz
    Kinghorn, Karina
    Quigley, Kaitlyn M.
    Kovacs-Kasa, Anita
    Annex, Brian H.
    Bautch, Victoria L.
    Mac Gabhann, Feilim
    PLOS COMPUTATIONAL BIOLOGY, 2024, 20 (02)
  • [47] NRP1 regulates HMGB1 in vascular endothelial cells under high homocysteine condition
    Ma, Yeshuo
    Zhang, Zhen
    Chen, Runtai
    Shi, Rui
    Zeng, Pingyu
    Chen, Ruifang
    Leng, Yiping
    Chen, Alex F.
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2019, 316 (05): : H1039 - H1046
  • [48] Cancer Exacerbates Ischemic Brain Injury Via Nrp1 (Neuropilin 1)-Mediated Accumulation of Regulatory T Cells Within the Tumor
    Wang, Long
    Zhou, Yuxi
    Yin, Jiemin
    Gan, Yu
    Wang, Xin
    Wen, Daxiang
    Thomson, Angus W.
    Hu, Xiaoming
    Yang, Liqun
    Stetler, R. Anne
    Li, Peiying
    Yu, Weifeng
    STROKE, 2018, 49 (11) : 2733 - 2742
  • [49] THE VALUE OF NT, TSP-2 AND NRP1 AS POTENTIAL DIAGNOSTIC BIOMARKERS IN ENDOMETRIAL CANCER
    Kozlowski, Mateusz
    Rotter, Iwona
    Turon-Skrzypinska, Agnieszka
    Borzyszkowska, Dominika
    Tkacz, Marta
    Tarnowski, Maciej
    Kwiatkowski, Sebastian
    Cymbaluk-Ploska, Aneta
    INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2023, 33 : A123 - A124
  • [50] microRNA-9 Acts as a Tumor Suppressor and Enhances Radio Sensitivity in Radio-Resistant A549 Cells by Targeting NRP1
    Xue, L.
    Xiong, K.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2017, 99 (02): : E628 - E628
12345