Separation of the Geometric Isomers of 4-Octyl-1,1a,2,3,4,5,6,6a-Octahydro-Cyclopropa[f]Indene-1-Carboxylic Acid Ethyl Ester and their Positional Isomers by Reversed-Phase HPLC

被引：0

作者：

Z. Hussain

机构：

[1] Max-Planck-Institut für Bioanorganische Chemie,

来源：

Chromatographia | 2006年 / 63卷

关键词：

Column liquid chromatography; Carbene adducts; Positional isomers; Geometric isomers separation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A high-performance liquid chromatography (HPLC) method for the separation of geometric and positional isomers is described. A gas chromatography-mass spectrometry (GC-MS) method for the detection and evaluation of various isomers is described. The developed method was able to separate the isomers in the purity range of 97.96% to 99.3% (GC analysis).

引用

页码：327 / 330

页数：3

共 4 条

[1] Separation of the geometric isomers of 4-octyl-1,1a,2,3,4,5,6,6a-octahydro-cyclopropa[f]indene-1-carboxylic acid ethyl ester and their positional isomers by reversed-phase HPLC
Hussain, Z
CHROMATOGRAPHIA, 2006, 63 (7-8) : 327 - 330
[2] Synthesis and stereochemical aspects of ethyl 1,1a,2,3,4,5,6,6a-octahydro-4-octylcyclopropa[f]indene-1-carboxylate
Hussain, Z
Koley, D
Hopf, H
HELVETICA CHIMICA ACTA, 2005, 88 (12) : 3263 - 3273
[3] rac-(1R, 1aR, 4S, 6aS)-Ethyl 4-carboxy-1,1a, 2,3,4,5,6,6a-octahydrocyclopropa[f]-indene-1-carboxylate
Jones, PG
Hopf, H
Hussain, Z
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2005, 61 : O3034 - O3035
[4] SENSITIVE STEREOSPECIFIC ASSAY OF WARFARIN IN PLASMA - REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC SEPARATION USING DIASTEREOISOMERIC ESTERS OF (-)-(1S,2R,4R)-ENDO-1,4,5,6,7,7-HEXACHLOROBICYCLO[2.2.1]-HEPT-5-ENE-2-CARBOXYLIC ACID
CARTER, SR
DUKE, CC
CUTLER, DJ
HOLDER, GM
JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1992, 574 (01): : 77 - 83

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