Polymer Nanoparticles Prepared by Supercritical Carbon Dioxide for in Vivo Anti-cancer Drug Delivery

被引：0
|
作者：
Maofang Hua
Xiufu Hua
机构：
[1] Lianyungang Maternal and Child Health Hospital,Department of Scientific Research and Development
[2] Tsinghua University,undefined
来源：
Nano-Micro Letters | 2014年 / 6卷
关键词：
Protein; Polymer; Nanoparticle; Drug delivery;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A new approach for producing polymer nanoparticles made of bovine serum albumin-poly(methyl methacrylate) conjugate by precipitating in supercritical CO2 is reported. The nanoparticles were loaded with the anti-tumor drug camptothecin. With albumin serving as a nutrient to cells, the drug-encapsulated nanoparticle shows an enhanced ability to kill cancer cells compared to that of the free drug in solution both in vitro and in vivo.
引用
收藏
页码：20 / 23
页数：3
相关论文
共 50 条
  • [1] Polymer Nanoparticles Prepared by Supercritical Carbon Dioxide for in Vivo Anti-cancer Drug Delivery
    Maofang Hua
    Xiufu Hua
    Nano-Micro Letters, 2014, (01) : 20 - 23
  • [2] Polymer Nanoparticles Prepared by Supercritical Carbon Dioxide for in Vivo Anti-cancer Drug Delivery
    Maofang Hua
    Xiufu Hua
    Nano-Micro Letters, 2014, 6 (01) : 20 - 23
  • [3] Polymer Nanoparticles Prepared by Supercritical Carbon Dioxide for in Vivo Anti-cancer Drug Delivery
    Hua, Maofang
    Hua, Xiufu
    NANO-MICRO LETTERS, 2014, 6 (01) : 20 - 23
  • [4] Carbon Dioxide-Generating PLG Nanoparticles for Controlled Anti-Cancer Drug Delivery
    Jang, Hyeon Jin
    Jeong, Eun Ju
    Lee, Kuen Yong
    PHARMACEUTICAL RESEARCH, 2018, 35 (03)
  • [5] Carbon Dioxide-Generating PLG Nanoparticles for Controlled Anti-Cancer Drug Delivery
    Hyeon Jin Jang
    Eun Ju Jeong
    Kuen Yong Lee
    Pharmaceutical Research, 2018, 35
  • [6] Cisplatin encapsulated nanoparticles from polymer blends for anti-cancer drug delivery
    Joshy, K. S.
    Augustine, Robin
    Hasan, Anwarul
    Zahid, Alap Ali
    Alex, Susan M.
    Dalvi, Yogesh B.
    Mraiche, Fatima
    Thomas, Sabu
    Kalarikkal, Nandakumar
    Chi, Hong
    NEW JOURNAL OF CHEMISTRY, 2022, 46 (12) : 5819 - 5829
  • [7] Measurement and thermodynamic modeling of solubility of Erlotinib hydrochloride, as an anti-cancer drug, in supercritical carbon dioxide
    Bazaei, Majid
    Honarvar, Bizhan
    Esfandiari, Nadia
    Sajadian, Seyed Ali
    Aboosadi, Zahra Arab
    FLUID PHASE EQUILIBRIA, 2023, 573
  • [8] Experimental data and thermodynamic modeling of solubility of Azathioprine, as an immunosuppressive and anti-cancer drug, in supercritical carbon dioxide
    Sodeifian, Gholamhossein
    Razmimanesh, Fariba
    Ardestani, Nedasadat Saadati
    Sajadian, Seyed Ali
    JOURNAL OF MOLECULAR LIQUIDS, 2020, 299
  • [9] Magnetic Nanoparticles and Thermally Responsive Polymer for Targeted Hyperthermia and Sustained Anti-Cancer Drug Delivery
    Wang, Sarah Y.
    Liu, Michelle C.
    Kang, Kyung A.
    OXYGEN TRANSPORT TO TISSUE XXXIV, 2013, 765 : 315 - 321
  • [10] Experimental solubility and modeling of Crizotinib (anti-cancer medication) in supercritical carbon dioxide
    Sodeifian, Gholamhossein
    Garlapati, Chandrasekhar
    Roshanghias, Armin
    SCIENTIFIC REPORTS, 2022, 12 (01)
12345