Islet amyloid formation is an important determinant for inducing islet inflammation in high-fat-fed human IAPP transgenic mice

被引：0

作者：

Daniel T. Meier

Mary Morcos

Thanya Samarasekera

Sakeneh Zraika

Rebecca L. Hull

Steven E. Kahn

机构：

[1] VA Puget Sound Health Care System (151),Division of Metabolism, Endocrinology and Nutrition, Department of Medicine

[2] University of Washington,undefined

来源：

Diabetologia | 2014年 / 57卷

关键词：

Chemokine; Cytokine; In vivo; Insulin secretion; Macrophage; NLRP3 inflammasome;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

页码：1884 / 1888

页数：4

共 50 条

[41] Male but not female mice develop systemic inflammation and insulin resistance when fed a high fat diet, resulting in increased islet blood flow and islet hypertrophy
Pettersson, U.
Jansson, L.
Phillipson, M.
JOURNAL OF VASCULAR RESEARCH, 2011, 48 : 124 - 124
[42] Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice
Westermark, G
Westermark, P
Eizirik, DL
Hellerström, C
Fox, N
Steiner, DF
Andersson, A
METABOLISM-CLINICAL AND EXPERIMENTAL, 1999, 48 (04): : 448 - 454
[43] Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets
J. F. Paulsson
A. Andersson
P. Westermark
G. T. Westermark
Diabetologia, 2006, 49 : 1237 - 1246
[44] EXPRESSION OF HUMAN IAPP AND AMYLOID FIBRIL FORMATION IN PANCREATIC-ISLETS FROM TRANSGENIC MICE
DEKONING, EJP
VERBEEK, JS
CAPEL, PA
MORRIS, JF
GUEST, PC
HUTTON, JC
CLARK, A
DIABETOLOGIA, 1994, 37 : A51 - A51
[45] Treatment with growth hormone and dexamethasone in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction
Couce, M
Kane, LA
OBrien, TD
Charlesworth, J
Soeller, W
McNeish, J
Kreutter, D
Roche, P
Butler, PC
DIABETES, 1996, 45 (08) : 1094 - 1101
[46] INTRACELLULAR AND EXTRACELLULAR AMYLOID FIBRILS ARE FORMED IN ISLETS FROM TRANSGENIC MICE EXPRESSING HUMAN ISLET AMYLOID POLYPEPTIDE
DEKONING, EJP
VERBEEK, JS
MORRIS, JF
CLARK, A
DIABETES, 1994, 43 : A67 - A67
[47] Intracellular amyloid-like deposits contain unprocessed pro-islet amyloid polypeptide (proIAPP) in beta cells of transgenic mice overexpressing the gene for human IAPP and transplanted human islets
Paulsson, JF
Andersson, A
Westermark, P
Westermark, GT
DIABETOLOGIA, 2006, 49 (06) : 1237 - 1246
[48] Induction of insulin resistance in mice transgenic for human islet amyloid polypeptide causes islet amyloidosis and beta-cell dysfunction.
Couce, M
Kane, LA
OBrien, TD
Soeller, W
Mcneish, J
Kreutter, D
Roche, P
Butler, PC
DIABETES, 1996, 45 : 134 - 134
[49] Increased amyloid fibril formation and beta cell toxicity of S20G mutant human islet amyloid polypeptide (IAPP)
Park, K
Jaikaran, ETAS
Clark, A
Verchere, CB
DIABETES, 2002, 51 : A386 - A386
[50] TRANSGENIC MICE OVERPRODUCING HUMAN ISLET AMYLOID POLYPEPTIDE HAVE INCREASED INSULIN STORAGE AND SECRETION
VERCHERE, CB
DALESSIO, DA
KAHN, SE
DIABETES, 1993, 42 : A10 - A10

← 1 2 3 4 5 →