Spectral contrast optical coherence tomography angiography enables single-scan vessel imaging

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作者
James A. Winkelmann
Aya Eid
Graham Spicer
Luay M. Almassalha
The-Quyen Nguyen
Vadim Backman
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[1] Northwestern University,Department of Biomedical Engineering
[2] Northwestern University,Department of Chemical and Biological Engineering
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Optical coherence tomography angiography relies on motion for contrast and requires at least two data acquisitions per pointwise scanning location. We present a method termed spectral contrast optical coherence tomography angiography using visible light that relies on the spectral signatures of blood for angiography from a single scan using endogenous contrast. We demonstrate the molecular sensitivity of this method, which enables lymphatic vessel, blood, and tissue discrimination.
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