Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity

被引:0
|
作者
Chun-ping Wan
Li-xin Gao
Li-fei Hou
Xiao-qian Yang
Pei-lan He
Yi-fu Yang
Wei Tang
Jian-min Yue
Jia Li
Jian-ping Zuo
机构
[1] Laboratory of Immunology and Virology,
[2] Shanghai University of Traditional Chinese Medicine,undefined
[3] State Key Laboratory of Drug Research,undefined
[4] Shanghai Institute of Materia Medica,undefined
[5] Chinese Academy of Sciences,undefined
[6] Central Laboratory,undefined
[7] No 1 Hospital Affiliated Yunnan University of Traditional Chinese Medicine,undefined
来源
关键词
immunomodulating agent; Bge; astragaloside II; CD45 PTPase; LCK; T cell; splenocyte; Src-family kinase; IFN-γ; IL-2; cyclophosphamide;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:522 / 530
页数:8
相关论文
共 50 条
  • [11] A Role for the Protein Tyrosine Phosphatase CD45 in Macrophage Adhesion through the Regulation of Paxillin Degradation
    St-Pierre, Joelle
    Ostergaard, Hanne L.
    PLOS ONE, 2013, 8 (07):
  • [12] THE REGULATION OF B-LYMPHOCYTE AND T-LYMPHOCYTE ACTIVATION BY THE TRANSMEMBRANE PROTEIN-TYROSINE-PHOSPHATASE CD45
    THOMAS, ML
    CURRENT OPINION IN CELL BIOLOGY, 1994, 6 (02) : 247 - 252
  • [13] REGULATION OF THE PROTEIN-TYROSINE PHOSPHATASE, CD45, BY PHOSPHORYLATION ON BOTH SERINE AND TYROSINE
    STOVER, DR
    WALSH, KA
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1993, : 315 - 315
  • [14] Structural basis for the function and regulation of the receptor protein tyrosine phosphatase CD45
    Nam, HJ
    Poy, F
    Saito, H
    Frederick, CA
    JOURNAL OF EXPERIMENTAL MEDICINE, 2005, 201 (03): : 441 - 452
  • [15] T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45
    Kozieradzki, I
    Kundig, T
    Kishihara, K
    Ong, CJ
    Chiu, D
    Wallace, VA
    Kawai, K
    Timms, E
    Ionescu, J
    Ohashi, P
    Marth, JD
    Mak, TW
    Penninger, JM
    JOURNAL OF IMMUNOLOGY, 1997, 158 (07): : 3130 - 3139
  • [16] Expression of CD45 lacking the catalytic protein tyrosine phosphatase domain modulates Lck phosphorylation and T cell activation
    Wang, YN
    Johnson, P
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (14) : 14318 - 14324
  • [17] Regulation of mast cell signaling through high-affinity IgE receptor by CD45 protein tyrosine phosphatase
    Murakami, K
    Sato, S
    Nagasawa, S
    Yamashita, T
    INTERNATIONAL IMMUNOLOGY, 2000, 12 (02) : 169 - 176
  • [18] Regulation of wedge-mediated inhibition of CD45 function by protein tyrosine phosphatase domain II
    Justement, LB
    Herrin, BR
    King, RG
    Wang, YN
    FASEB JOURNAL, 2002, 16 (04): : A701 - A701
  • [19] Modulation of CD45 tyrosine phosphatase activity by antigen
    Paz, FL
    Galgani, M
    D'Oro, U
    Matarese, G
    Masci, AM
    Zappacosta, S
    Racioppi, L
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2001, 31 (03) : 777 - 782
  • [20] ACTIVATION OF TYROSINE PHOSPHORYLATION IN HUMAN T-CELLS VIA THE CD2 PATHWAY - REGULATION BY THE CD45 TYROSINE PHOSPHATASE
    SAMELSON, LE
    FLETCHER, MC
    LEDBETTER, JA
    JUNE, CH
    JOURNAL OF IMMUNOLOGY, 1990, 145 (08): : 2448 - 2454