CDK4/6 inhibitor-SHR6390 exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated Rb and inducing G1 cell cycle arrest

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作者
Jiayuan Wang
Qingqing Li
Jiajia Yuan
Jingyuan Wang
Zuhua Chen
Zhentao Liu
Zhongwu Li
Yumei Lai
Jing Gao
Lin Shen
机构
[1] Peking University Cancer Hospital and Institute,Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing)
[2] Peking University Cancer Hospital and Institute,Department of Pathology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing)
关键词
CDK4/6 inhibitor; ESCC; Cell cycle arrest; pRb;
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