Effector CD8 T cells dedifferentiate into long-lived memory cells

被引：0
|
作者：
Ben Youngblood
J. Scott Hale
Haydn T. Kissick
Eunseon Ahn
Xiaojin Xu
Andreas Wieland
Koichi Araki
Erin E. West
Hazem E. Ghoneim
Yiping Fan
Pranay Dogra
Carl W. Davis
Bogumila T. Konieczny
Rustom Antia
Xiaodong Cheng
Rafi Ahmed
机构：
[1] Emory Vaccine Center,Department of Microbiology and Immunology
[2] Emory University School of Medicine,Department of Immunology
[3] Emory University School of Medicine,Department of Urology
[4] St. Jude Children’s Research Hospital,Department of Computational Biology
[5] Emory University School of Medicine,Department of Biology
[6] St. Jude Children’s Research Hospital,Department of Biochemistry
[7] Emory University,Department of Molecular and Cellular Oncology
[8] Emory University School of Medicine,undefined
[9] The University of Texas MD Anderson Cancer Center,undefined
来源：
Nature | 2017年 / 552卷
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学科分类号：
摘要：
DNA methylation profiling of virus-specific T cells during acute viral infection in mice provides evidence that a fate-permissive subset of effector CD8 T cells dedifferentiates into long-lived memory T cells.
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页码：404 / 409
页数：5
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