Effector CD8 T cells dedifferentiate into long-lived memory cells

被引：0

作者：

Ben Youngblood

J. Scott Hale

Haydn T. Kissick

Eunseon Ahn

Xiaojin Xu

Andreas Wieland

Koichi Araki

Erin E. West

Hazem E. Ghoneim

Yiping Fan

Pranay Dogra

Carl W. Davis

Bogumila T. Konieczny

Rustom Antia

Xiaodong Cheng

Rafi Ahmed

机构：

[1] Emory Vaccine Center,Department of Microbiology and Immunology

[2] Emory University School of Medicine,Department of Immunology

[3] Emory University School of Medicine,Department of Urology

[4] St. Jude Children’s Research Hospital,Department of Computational Biology

[5] Emory University School of Medicine,Department of Biology

[6] St. Jude Children’s Research Hospital,Department of Biochemistry

[7] Emory University,Department of Molecular and Cellular Oncology

[8] Emory University School of Medicine,undefined

[9] The University of Texas MD Anderson Cancer Center,undefined

来源：

Nature | 2017年 / 552卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

DNA methylation profiling of virus-specific T cells during acute viral infection in mice provides evidence that a fate-permissive subset of effector CD8 T cells dedifferentiates into long-lived memory T cells.

引用

页码：404 / 409

页数：5

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[1] Effector CD8 T cells dedifferentiate into long-lived memory cells
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Ahn, Eunseon
Xu, Xiaojin
Wieland, Andreas
Araki, Koichi
West, Erin E.
Ghoneim, Hazem E.
Fan, Yiping
Dogra, Pranay
Davis, Carl W.
Konieczny, Bogumila T.
Antia, Rustom
Cheng, Xiaodong
Ahmed, Rafi
[J]. NATURE, 2017, 552 (7685) : 404 - +
[2] Unique Properties of Long-lived Effector CD8 T cells
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[3] Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
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