Lupus nephritis: lessons from murine models

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Anne Davidson
Cynthia Aranow
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[1] Center for Autoimmune and Musculoskeletal Diseases,
[2] Feinstein Institute for Medical Research,undefined
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Treatment of renal disease associated with systemic lupus erythematosus remains inadequate despite advances in our understanding of the disease pathogenesis. As discussed in this Review, clinical trials are underway for a number of therapeutic agents shown to be successful in murine lupus. In addition, insights gleaned from animal studies could lead to new strategies for the treatment of lupus nephritis in humans.
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页码:13 / 20
页数:7
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