While bone marrow transplantation has long been established as an effective approach to the clinical management of a variety of malignant and nonmalignant diseases, the future application of pluripotent stem cells in transplant settings promises to deliver this therapy to a much broader range of indications. In this review, I summarize the emerging field of embryonic stem cell biology in the context of potential clinical applications and regulatory issues.
机构:University of Toronto,Institute of Biomaterials and Biomedical Engineering (IBBME) and The Donnelly Centre for Cellular and Biomolecular Research (CCBR)
Mukul Tewary
Nika Shakiba
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机构:University of Toronto,Institute of Biomaterials and Biomedical Engineering (IBBME) and The Donnelly Centre for Cellular and Biomolecular Research (CCBR)
Nika Shakiba
Peter W. Zandstra
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机构:University of Toronto,Institute of Biomaterials and Biomedical Engineering (IBBME) and The Donnelly Centre for Cellular and Biomolecular Research (CCBR)
机构:
Univ Nebraska Med Ctr, Dept Pharmacol, Omaha, NE 68198 USA
Univ Nebraska Med Ctr, Dept Expt Neurosci Pathol Microbiol & Family Med, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Dept Pharmacol, Omaha, NE 68198 USA
Zheng, Jialin C.
Tong, Zenghan
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Univ Nebraska Med Ctr, Dept Pharmacol & Expt Neurosci, Omaha, NE 68198 USAUniv Nebraska Med Ctr, Dept Pharmacol, Omaha, NE 68198 USA
机构:
Georgia Cancer Center, Augusta University, Augusta, 30912, GA
Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, 30912, GAGeorgia Cancer Center, Augusta University, Augusta, 30912, GA
Alptekin A.
Ye B.
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Georgia Cancer Center, Augusta University, Augusta, 30912, GAGeorgia Cancer Center, Augusta University, Augusta, 30912, GA
Ye B.
Ding H.-F.
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机构:
Georgia Cancer Center, Augusta University, Augusta, 30912, GA
Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, 30912, GA
Department of Pathology, Medical College of Georgia, Augusta University, Augusta, 30912, GAGeorgia Cancer Center, Augusta University, Augusta, 30912, GA
机构:
Northwestern Univ, Dept Chem & Biol Engn, Evanston, IL 60208 USANorthwestern Univ, Dept Chem & Biol Engn, Evanston, IL 60208 USA
Dellatore, Shara M.
Garcia, A. Sofia
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Northwestern Univ, Dept Chem & Biol Engn, Evanston, IL 60208 USANorthwestern Univ, Dept Chem & Biol Engn, Evanston, IL 60208 USA
Garcia, A. Sofia
Miller, William M.
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Northwestern Univ, Dept Chem & Biol Engn, Evanston, IL 60208 USA
Northwestern Univ, Robert H Laurie Comprehens Canc Ctr, Chicago, IL 60611 USANorthwestern Univ, Dept Chem & Biol Engn, Evanston, IL 60208 USA