Bursopentin (BP5) induces G1 phase cell cycle arrest and endoplasmic reticulum stress/mitochondria-mediated caspase-dependent apoptosis in human colon cancer HCT116 cells

被引:0
|
作者
Jing Li
Tian-xiang Li
Yao Ma
Yong Zhang
De-yuan Li
Hai-rong Xu
机构
[1] Yangzhou University,Institute of Translational Medicine, Medical College
[2] Yangzhou University,Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases
[3] Kangda College of Nanjing Medical University,Department of Clinical Medicine
[4] Nanjing Agricultural University,Key Lab of Animal Disease Diagnosis and Immunology, Ministry of Agriculture, College of Veterinary Medicine
[5] Yangzhou University,Jiangsu Co
来源
关键词
Apoptosis; Endoplasmic reticulum stress; G1 cell cycle arrest; Mitochondrial pathway; Reactive oxygen species;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Scutellarein from Scutellaria barbata induces apoptosis of human colon cancer HCT116 cells through the ROS-mediated mitochondria-dependent pathway
    Guo, Fei
    Yang, Feng
    Zhu, Yan-Hong
    NATURAL PRODUCT RESEARCH, 2019, 33 (16) : 2372 - 2375
  • [32] Platinum (IV) complex LA-12 induces cell cycle arrest and phase specific apoptosis in colon carcinoma cells HCT116
    Blanarova, O.
    Jelinkova, I.
    Jendzelovsky, R.
    Soucek, K.
    Hofmanova, J.
    Sova, P.
    Kozubik, A.
    EJC SUPPLEMENTS, 2008, 6 (12): : 89 - 89
  • [33] Stephanthraniline A suppresses proliferation of HCT116 human colon cancer cells through induction of caspase-dependent apoptosis, dysregulation of mitochondrial function, cell cycle arrest and regulation of Akt/p38 signaling pathways
    Wang, Lu
    Yao, Li
    Li, Xiaoyu
    Chen, Juan
    Lou, Chenghua
    Wang, Yiqi
    JOURNAL OF TOXICOLOGICAL SCIENCES, 2019, 44 (7-9): : 523 - 533
  • [34] Morus Rubra Extract Induces Cell Cycle Arrest and Apoptosis in Human Colon Cancer Cells Through Endoplasmic Reticulum Stress and Telomerase
    Demir, Selim
    Turan, Ibrahim
    Aliyazicioglu, Yuksel
    Kilinc, Kagan
    Yaman, Serap Ozer
    Demir, Elif Ayazoglu
    Arslan, Ayse
    Mentese, Ahmet
    Deger, Orhan
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2017, 69 (01): : 74 - 83
  • [35] Propyl gallate inhibits the growth of HeLa cells via caspase-dependent apoptosis as well as a G1 phase arrest of the cell cycle
    Han, Yong Hwan
    Moon, Hwa Jin
    You, Bo Ra
    Kim, Sung Zoo
    Kim, Suhn Hee
    Park, Woo Hyun
    ONCOLOGY REPORTS, 2010, 23 (04) : 1153 - 1158
  • [36] Decursin Induces G1 Cell Cycle Arrest and Apoptosis through Reactive Oxygen Species-Mediated Endoplasmic Reticulum Stress in Human Colorectal Cancer Cells in In Vitro and Xenograft Models
    Kim, Danbee
    Go, Seok-Ho
    Song, Yeeun
    Lee, Dong-Keon
    Park, Jeong-Ran
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (18)
  • [37] Novel HDACi, MHY446, induces apoptosis via regulation of mitochondria-endoplasmic reticulum interaction in HCT116 human colorectal cancer cells
    Kim, N. D.
    Ahn, Y. R.
    Kang, Y. J.
    Sung, B.
    Jang, J. Y.
    Kim, M. J.
    ANNALS OF ONCOLOGY, 2019, 30
  • [38] Sulforaphane Induces Cell Death Through G2/M Phase Arrest and Triggers Apoptosis in HCT 116 Human Colon Cancer Cells
    Liu, Kuo-Ching
    Shih, Ting-Ying
    Kuo, Chao-Lin
    Ma, Yi-Shih
    Yang, Jiun-Long
    Wu, Ping-Ping
    Huang, Yi-Ping
    Lai, Kuang-Chi
    Chung, Jing-Gung
    AMERICAN JOURNAL OF CHINESE MEDICINE, 2016, 44 (06): : 1289 - 1310
  • [39] Effect of Acacia concinna Extract on Apoptosis Induction Associated with Endoplasmic Reticulum Stress and Modulated Intracellular Signaling Pathway in Human Colon HCT116 Cancer Cells
    Sitthisuk, Pornnapa
    Innajak, Sukanda
    Poorahong, Watcharaporn
    Samosorn, Siritron
    Dolsophon, Kulvadee
    Watanapokasin, Ramida
    NUTRIENTS, 2024, 16 (21)
  • [40] Bromuconazole fungicide induces cell cycle arrest and apoptotic cell death in cultured human colon carcinoma cells (HCT116) via oxidative stress process
    Rjiba-Touati, Karima
    Ayed-Boussema, Imen
    Hamdi, Hiba
    Azzebi, Awatef
    Abid, Salwa
    BIOMARKERS, 2022, 27 (07) : 659 - 670