Infrared absorption spectra of human malignant tumor tissues

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作者
I. V. Skornyakov
G. B. Tolstorozhev
V. A. Butra
机构
[1] National Academy of Sciences of Belarus,B. I. Stepanov Institute of Physics
[2] Oncomorphology Department of the City Clinical and Anatomic Pathology Service,undefined
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malignant neoplasm; IR spectrum; protein; structure; hydrogen bond;
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摘要
We used infrared spectroscopy methods to study the molecular structure of tissues from human organs removed during surgery. The IR spectra of the surgical material from breast, thyroid, and lung are compared with data from histological examination. We show that in malignant neoplasms, a change occurs in the hydrogen bonds of protein macromolecules found in the tissue of the studied organs. We identify the spectral signs of malignant pathology.
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