Regulatory B cells—IL-35 and IL-21 regulate the regulators

被引：0

作者：

Thomas F. Tedder

Warren J. Leonard

机构：

[1] Duke University Medical Center,Department of Immunology

[2] Laboratory of Molecular Immunology and the Immunology Center,undefined

[3] National Heart,undefined

[4] Lung,undefined

[5] and Blood Institute,undefined

[6] National Institutes of Health,undefined

来源：

Nature Reviews Rheumatology | 2014年 / 10卷

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学科分类号：

摘要：

IL-21 regulates the activity and number of IL-10-producing regulatory B cells (B10 cells) that modulate immune responses and limit diverse autoimmune diseases. A new study demonstrates that IL-35 has a similar function. Identifying regulatory circuits that control B10-cell function in vivo might open the door to future treatments for autoimmune diseases.

引用

页码：452 / 453

页数：1

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