Regulatory B cells—IL-35 and IL-21 regulate the regulators

被引：0
|
作者：
Thomas F. Tedder
Warren J. Leonard
机构：
[1] Duke University Medical Center,Department of Immunology
[2] Laboratory of Molecular Immunology and the Immunology Center,undefined
[3] National Heart,undefined
[4] Lung,undefined
[5] and Blood Institute,undefined
[6] National Institutes of Health,undefined
来源：
Nature Reviews Rheumatology | 2014年 / 10卷
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摘要：
IL-21 regulates the activity and number of IL-10-producing regulatory B cells (B10 cells) that modulate immune responses and limit diverse autoimmune diseases. A new study demonstrates that IL-35 has a similar function. Identifying regulatory circuits that control B10-cell function in vivo might open the door to future treatments for autoimmune diseases.
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页码：452 / 453
页数：1
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