Antenatal depression among women with gestational diabetes mellitus: a pilot study

Pregnancy is a highly stressful period in a woman's life that can also be associated with mental health problems such as depression. Depression is reported in about 16% of pregnant women whereas and such prevalence can double in LMICs (e.g., Bangladesh). In addition, gestational diabetes mellitus (GDM) has emerged as a common condition affecting approximately 10% of all pregnancies. GDM has also been associated with adverse mental health outcomes, particularly depression. GDM women with antenatal depression are not only at increased risk of poorer quality of life, but are also at increased risk of adverse pregnancy and fetal outcomes, particularly in LMIC. This study investigates the prevalence of depressive symptoms among Bangladeshi pregnant women diagnosed with GDM. It is found that depression was detectable in 36.2% subjects. In addition, a history of reproductive health-related issues (i.e., abortion, neonatal death) and uncontrolled glycemic status were associated with increased risk of depressive disorders. Considering the negative effects of both GDM and depression on pregnancy-related outcomes, early screening of these conditions should be pursued, preferably once every trimester over the duration of the pregnancy.