Inorganic Polyphosphate and Cancer

被引：0
|
作者：
E. V. Kulakovskaya
M. Yu. Zemskova
T. V. Kulakovskaya
机构：
[1] Russian Academy of Sciences,Skryabin Institute of Biochemistry and Physiology of Microorganisms
[2] Research and Education Center of Pushchino,Moscow State Regional University
来源：
Biochemistry (Moscow) | 2018年 / 83卷
关键词：
inorganic polyphosphates; cancer; metastasis; cell motility; h-prune protein; mTOR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
This review presents data on the relationship between inorganic polyphosphate metabolism and carcinogenesis including participation of polyphosphates in the regulation of activity of mTOR and other proteins involved in carcinogenesis, the role of h-prune protein (human polyphosphatase) in cell migration and metastasis formation, the prospects for using polyphosphates and inhibitors of polyphosphate metabolism enzymes as agents for controlling cell proliferation and migration.
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页码：961 / 968
页数：7
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