The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

被引:0
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作者
Wataru Ise
Masako Kohyama
Barbara U Schraml
Tingting Zhang
Bjoern Schwer
Uttiya Basu
Frederick W Alt
Jun Tang
Eugene M Oltz
Theresa L Murphy
Kenneth M Murphy
机构
[1] Washington University School of Medicine,Department of Pathology and Immunology
[2] Howard Hughes Medical Institute,undefined
[3] The Children's Hospital,undefined
[4] the Immune Disease Institute and the Harvard Medical School,undefined
来源
Nature Immunology | 2011年 / 12卷
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摘要
The transcription factor BATF is known to control switched antibody responses. Murphy and colleagues show that BATF functions at multiple hierarchical levels in follicular helper T cells and B cells to regulate these responses.
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页码:536 / 543
页数:7
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