Plasticity of Renin Cells in the Kidney Vasculature

被引：0
|
作者：
R. Ariel Gomez
Maria Luisa S. Sequeira Lopez
机构：
[1] University of Virginia School of Medicine,
[2] Child Health Research Center,undefined
来源：
Current Hypertension Reports | 2017年 / 19卷
关键词：
Cell fate; Cell identity; Cell memory; Cell number; Recruitment;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
During development, renin cells are precursors for arteriolar smooth muscle, mesangial cells, and interstitial pericytes. Those seemingly differentiated descendants retain the memory to re-express renin when there is a threat to homeostasis. Understanding how such molecular memory is constructed and regulated would be crucial to comprehend cell identity which is, in turn, intimately linked to homeostasis.
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