Palladium-catalysed synthesis of triaryl(heteroaryl)methanes

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作者：
Shuguang Zhang
Byeong-Seon Kim
Chen Wu
Jianyou Mao
Patrick J. Walsh
机构：
[1] Roy and Diana Vagelos Laboratories,Department of Chemistry
[2] University of Pennsylvania,undefined
[3] Institute of Advanced Synthesis,undefined
[4] School of Chemistry and Molecular Engineering,undefined
[5] Jiangsu National Synergetic Innovation Center for Advanced Materials,undefined
[6] Nanjing Tech University,undefined
来源：
Nature Communications | / 8卷
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摘要：
Tetraarylmethane derivatives are desirable for a variety of applications, but difficult to access with modern C–C bond-forming reactions. Here we report a straightforward method for palladium-catalysed arylation of aryl(heteroaryl)methanes and diaryl(heteroaryl)methanes with aryl chlorides. This reaction enables introduction of various aryl groups to construct triaryl(heteroaryl)methanes via a C–H functionalization in good to excellent yield, and represents the first step towards a general transition metal catalysed synthesis of tetraarylmethanes.
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