The mucosal milieu creates tolerogenic dendritic cells and TR1 and TH3 regulatory cells

被引:0
|
作者
Howard L. Weiner
机构
[1] Harvard Medical School,
[2] Center for Neurologic Diseases,undefined
[3] Brigham and Women's Hospital,undefined
来源
Nature Immunology | 2001年 / 2卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Certain types of regulatory T cells are preferentially induced at mucosal surfaces to maintain tolerance. However, the mechanisms involved in their induction are unclear. New evidence suggests DCs orchestrate this mucosal tolerogenic immune response.
引用
收藏
页码:671 / 672
页数:1
相关论文
共 50 条
  • [41] Regulatory T Cells and Tolerogenic Dendritic Cells as Critical Immune Modulators in Atherogenesis
    Sasaki, Naoto
    Yamashita, Tomoya
    Kasahara, Kazuyuki
    Takeda, Masafumi
    Hirata, Ken-ichi
    [J]. CURRENT PHARMACEUTICAL DESIGN, 2015, 21 (09) : 1107 - 1117
  • [42] T-regulatory-1 (Tr1) cells prevent colitis induced by enteric bacterial antigen-reactive pathogenic Th1 cells.
    Cong, YZ
    Weaver, CT
    Lazenby, A
    Sundberg, JP
    Elson, CO
    [J]. GASTROENTEROLOGY, 2000, 118 (04) : A683 - A683
  • [43] Tumor-derived Adenosine Enhances Generation of Adaptive Regulatory T Cells (Tr1)
    Mandapathil, Magis
    Lang, Stephan
    Jackson, Edwin K.
    Gorelik, Elieser
    Whiteside, Theresa L.
    [J]. JOURNAL OF IMMUNOTHERAPY, 2009, 32 (09) : 998 - 998
  • [44] RAPAMYCIN EXPANDS AND CONFERS RESISTANCE TO APOPTOSIS OF HUMAN INDUCIBLE REGULATORY T CELLS (TR1)
    Bergmann, C.
    Wild, C. A.
    Hoffmann, T. K.
    Lang, S.
    Whiteside, T. L.
    [J]. EUROPEAN JOURNAL OF INFLAMMATION, 2013, 11 (02) : 447 - 457
  • [45] Increased Expression of Regulatory Tr1 Cells in Recurrent Hepatitis C after Liver Transplantation
    Carpentier, A.
    Conti, F.
    Stenard, F.
    Aoudjehane, L.
    Miroux, C.
    Podevin, P.
    Morales, O.
    Chouzenoux, S.
    Scatton, O.
    Groux, H.
    Auriault, C.
    Calmus, Y.
    Pancre, V.
    Delhem, N.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2009, 9 (09) : 2102 - 2112
  • [46] Tolerogenic Dendritic Cells for Regulatory T Cell Induction in Man
    Raker, Verena K.
    Domogalla, Matthias P.
    Steinbrink, Kerstin
    [J]. FRONTIERS IN IMMUNOLOGY, 2015, 6
  • [47] Foxp3 Tr1 regulatory T cells as a therapeutic antidote in reversing cockroach-induced asthma
    McGee, HS
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2006, 117 (02) : S241 - S241
  • [48] Modification of dendritic cells by Th3 cells derived from TGF-beta transgenic mice.
    Carrier, Yijun
    Weiner, Howard
    [J]. CLINICAL IMMUNOLOGY, 2006, 119 : S114 - S114
  • [49] Tolerogenic dendritic cells for Type 1 diabetes
    Giannoukakis, Nick
    [J]. IMMUNOTHERAPY, 2013, 5 (06) : 569 - 571
  • [50] Characterization of T Regulatory Type 1 (Tr1) Cells in Naive and Transplanted Non-Human Primates
    Yu, R.
    Tonsho, M.
    Spencer, P.
    Bernard-Stoecklin, S.
    Benichou, G.
    Madsen, J.
    [J]. AMERICAN JOURNAL OF TRANSPLANTATION, 2016, 16 : 414 - 414